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MRM-GRE法を用いた肝臓の鉄含有量および脂肪含有率の同時測定
http://hdl.handle.net/2297/24703
http://hdl.handle.net/2297/247035c6b6233-cbf8-44d9-8da9-df4b913e514b
名前 / ファイル | ライセンス | アクション |
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ME-PR-MIYATI-T-64.pdf (731.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | MRM-GRE法を用いた肝臓の鉄含有量および脂肪含有率の同時測定 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Simultaneous R2* and Fat Fraction Determination of the Liver with Modulus and Real Multiple Gradient-echo MRI | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
小野, 絵理
× 小野, 絵理× 宮地, 利明× 大野, 直樹× 笠井, 治昌× 原, 真咲× 芝本, 雄太× 川野, 誠× 朝日, 美幸 |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域保健学系 | |||||
書誌情報 |
医用画像情報学会雑誌 = Japan Society of Imaging and Information Sciences in Medicine 巻 26, 号 3, p. 64-67, 発行日 2009-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0910-1543 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10156808 | |||||
出版者 | ||||||
出版者 | 医用画象情報学会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We evaluated the R2* (iron content) and fat fraction of the liver tissue simultaneously using modulus and real multiple gradient-echo (MRM-GRE) sequence. On a 1.5-T MRI, modulus images of 7-9 gradient-echoes were obtained by MRM-GRE sequence at a time. A real part of the first echo image was also reconstructed to differentiate below and above the 50 percent fat fraction. The fat fraction and R2* were obtained from the parameters of a theoretically fitted formula with each echo signal. R2* and fat fraction were measured with MRM-GRE in the phantom and the liver in normal volunteers (n=6) and patients with fatty liver (n=4) . MRI-derived fat fraction of the phantom was in good agreement with the actual value, and R2* of the phantom showed a strongly positive correlation with the actual iron content. MRI-derived fat fraction in fatty liver was significantly higher than that in the normal volunteers. However, no significant difference in R2* was found between fatty liver and normal volunteers. These results show that the MRM-GRE enables to differentiate the causes of signal reduction whether increasing R2*or increasing fat fraction. The MRM-GRE method makes it possible to simply and accurately assess the fat content and the iron content. | |||||
権利 | ||||||
権利情報 | Copyright (c) 2009 by Japan Society of Medical Imaging and Information Sciences | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.mii-sci.jp/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/130000138572 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.jstage.jst.go.jp/article/mii/26/3/26_64/_article |