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成人MRSA患者におけるバンコマイシンの初期投与量推定法の比較検討
http://hdl.handle.net/2297/36368
http://hdl.handle.net/2297/3636859893112-d849-4da3-a237-325ee9445d01
名前 / ファイル | ライセンス | アクション |
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HO-PR-MIYAMOTO-K-530.pdf (1.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | 成人MRSA患者におけるバンコマイシンの初期投与量推定法の比較検討 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Comparative Examination of the Initial Dosage Setting of Vancomycin Therapy in the Adult MRSA Patients | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
寺町, ひとみ
× 寺町, ひとみ× 畠山, 裕充× 松下, 良× 今井, 幸夫× 宮本, 謙一× 辻, 彰 |
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書誌情報 |
医療薬学 = Japanese Journal of Pharmaceutical Health Care and Sciences 巻 28, 号 6, p. 530-540, 発行日 2002-10-10 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1346-342X | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11527197 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.5649/jjphcs.28.530 | |||||
出版者 | ||||||
出版者 | 日本医療薬学会 = Japanese Society of Pharmaceutical Health Care and Sciences | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The department of pharmacy which is a member of the Infection Control Committee in Kouseiren Chu-nou Hospital provided a systematic program of vancomycin (VCM) therapeutic drug monitoring (TDM) and consultations regarding the suitable dose and administration interval etc. of VCM for both patients and physicians. However, in many cases the initial dosage and dose interval were empirically decided by the physician. In the present study, we retrospectively examined three nomogrames that were recommended as the rough standard for determining the initial dosage and dose interval, in comparison to the Bayesian method, based on our hospital data collected from adult MRSA patients. We also compared our findings with the Moellering's method, Matzke's method, Maeda's method and the Population mean methods. Maeda's method did not predict the serum trough and peak levels that reach poisonous ranges. Maeda's method was found to be a safe method. In addition, Maeda's method was found to reach the therapeutic ranges the most frequently of the four methods. Furthermore, the calculations for Maeda's method were simpler than the other three methods. Accordingly, it is possible to easily calculate the initial dosage and dose interval in the clinical field. The serum VCM concentrations should thus be measured for each patient, as soon as possible, to correct the dosage using the Bayesian forecasting technique, because the therapeutic ranges sometimes deviate from the predicted range. | |||||
権利 | ||||||
権利情報 | Copyright © JSPHCS Japanese Society of Pharmaceutical Health Care and Sciences | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.jsphcs.jp/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/jjphcs/-char/ja/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/110001166641/ |