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Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis
http://hdl.handle.net/2297/39139
http://hdl.handle.net/2297/391390f9aade3-3149-4f7e-bf5d-af8d64d4af6b
名前 / ファイル | ライセンス | アクション |
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PH-PR-SHIMADA-T-2124.pdf (4.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | Advantages and disadvantages of hyperbaric oxygen treatment in mice with obesity hyperlipidemia and steatohepatitis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tsuneyama, Koichi
× Tsuneyama, Koichi× Chen, Yen-Chen× Fujimoto, Makoto× Sasaki, Yoshiyuki× Suzuki, Wataru× Shimada, Tsutomu× Iizuka, Seiichi× Nagata, Mitsunobu× Aburada, Masaki× Chen, Shao-Yuan |
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書誌情報 |
The Scientific World Journal 巻 11, 号 380236, p. 2124-2135, 発行日 2011-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1537-744X | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1100/2011/380236 | |||||
出版者 | ||||||
出版者 | Scientific World / Hindawi Publishing Corporation | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The effect of hyperbaric oxygen treatment (HBOT) was examined using MSG mice, which are an animal model of obesity, hyperlipidemia, diabetes, and nonalcoholic fatty liver disease. Nineteen MSG male mice were divided into HBOT treated and control groups at 12 weeks of ages. The HBOT group was treated with hyperbaric oxygen from 12 to 14 weeks (first phase) and then from 16 to 18 weeks (second phase). Interestingly, the body weight of the HBOT group was significantly lower (P < 0.01) than that of the control group. In contrast, the serum lipid level did not show significant changes between the two groups. As for the effects of increasing oxidative stress, the liver histology of the HBOT group showed severer cellular damage and aberrant TNF- expression. HBOT has the advantage of improving obesity in patients with metabolic syndrome, but the fault of causing organ damage by increasing oxidative stress. Copyright 2011 Koichi Tsuneyama et al. | |||||
権利 | ||||||
権利情報 | Copyright © 2011 Koichi Tsuneyama et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.hindawi.com/journals/tswj/2011/380236/ |