WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "9cd19eb6-ef76-4f4d-924c-3c9468993dc0"}, "_deposit": {"created_by": 3, "id": "38376", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "38376"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00038376", "sets": ["2983"]}, "author_link": ["62056", "20081"], "item_14_biblio_info_13": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-03-01", "bibliographicIssueDateType": "Issued"}, "bibliographicVolumeNumber": "2011年度", "bibliographic_titles": [{"bibliographic_title": "金沢大学大学院医薬保健学総合研究科博士論文, 10p."}]}]}, "item_14_description_26": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The purpose of this study was to investigate the effect of reloading on atrophied muscle and the time course of hypertrophy and regeneration. Forty-nine male Wistar rats were randomly assigned to groups for hindlimb suspension (HS), hindlimb suspension and reloading (R), or control (C0). Rats in the HS group were suspended for 14 days. Rats in the R group were randomly divided into five subgroups for different post-hindlimb-suspension recovery times. Briefly, each subgroup was suspended for 14 days and given 1 day of reloading (R1), 3 days of reloading (R3), 7 days of reloading (R7), 10 days of reloading (R10), or 14 days of reloading (R14). Myonuclear numbers were significantly decreased in the groups with hindlimb suspension and 1 day and 3 days of reloading compared with that in the control group. We focused on the processes of change of mean myofiber cross-sectional area and myonuclear domain size; the degrees of increase of both indexes were limited until 3 days of reloading, and significantly increased after 7 days of reloading. An important finding of the current study was that the processes of muscle hypertrophy and regeneration did not show uniform change. In addition, there were differences in the ratio of increase among the stages of hypertrophy and regeneration. Therefore, consideration of the duration and method of physiotherapeutic intervention for atrophied muscle on the basis of the process of hypertrophy and regeneration is needed to provide more effective physiotherapy.", "subitem_description_type": "Abstract"}]}, "item_14_description_27": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "Thesis of Zushi, Kazumi / 都志 和美 博士学位論文(金沢大学 / 大学院医学系研究科)", "subitem_description_type": "Other"}]}, "item_14_publisher_22": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "金沢大学"}]}, "item_14_version_type_30": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Zushi, Kazumi"}], "nameIdentifiers": [{"nameIdentifier": "62056", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamazaki, Toshiaki"}], "nameIdentifiers": [{"nameIdentifier": "20081", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "00220319", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=00220319"}, {"nameIdentifier": "00220319", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=00220319"}, {"nameIdentifier": "00220319", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000000220319"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-05"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Thesis-2011-ZUSHI-K-10.pdf", "filesize": [{"value": "137.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 137500.0, "url": {"label": "Thesis-2011-ZUSHI-K-10.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/38376/files/Thesis-2011-ZUSHI-K-10.pdf"}, "version_id": "814cf7c1-e652-47cd-be2e-41f4de6942d9"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "hindlimb suspension", "subitem_subject_scheme": "Other"}, {"subitem_subject": "reloading", "subitem_subject_scheme": "Other"}, {"subitem_subject": "time course", "subitem_subject_scheme": "Other"}, {"subitem_subject": "myofiber cross-sectional area", "subitem_subject_scheme": "Other"}, {"subitem_subject": "myonuclear", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change"}]}, "item_type_id": "14", "owner": "3", "path": ["2983"], "permalink_uri": "http://hdl.handle.net/2297/30569", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-05"}, "publish_date": "2017-10-05", "publish_status": "0", "recid": "38376", "relation": {}, "relation_version_is_last": true, "title": ["The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change"], "weko_shared_id": -1}
The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change
http://hdl.handle.net/2297/30569
http://hdl.handle.net/2297/305693c621947-f7aa-416f-8098-0ca770d9b64c
名前 / ファイル | ライセンス | アクション |
---|---|---|
Thesis-2011-ZUSHI-K-10.pdf (137.5 kB)
|
|
Item type | 学位論文 / Thesis or Dissertation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | The effect of reloading on disuse muscle atrophy: Time course of hypertrophy and regeneration focusing on the myofiber cross-sectional area and myonuclear change | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||
資源タイプ | thesis | |||||
著者 |
Zushi, Kazumi
× Zushi, Kazumi× Yamazaki, Toshiaki |
|||||
書誌情報 |
金沢大学大学院医薬保健学総合研究科博士論文, 10p. 巻 2011年度, 発行日 2012-03-01 |
|||||
出版者 | ||||||
出版者 | 金沢大学 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The purpose of this study was to investigate the effect of reloading on atrophied muscle and the time course of hypertrophy and regeneration. Forty-nine male Wistar rats were randomly assigned to groups for hindlimb suspension (HS), hindlimb suspension and reloading (R), or control (C0). Rats in the HS group were suspended for 14 days. Rats in the R group were randomly divided into five subgroups for different post-hindlimb-suspension recovery times. Briefly, each subgroup was suspended for 14 days and given 1 day of reloading (R1), 3 days of reloading (R3), 7 days of reloading (R7), 10 days of reloading (R10), or 14 days of reloading (R14). Myonuclear numbers were significantly decreased in the groups with hindlimb suspension and 1 day and 3 days of reloading compared with that in the control group. We focused on the processes of change of mean myofiber cross-sectional area and myonuclear domain size; the degrees of increase of both indexes were limited until 3 days of reloading, and significantly increased after 7 days of reloading. An important finding of the current study was that the processes of muscle hypertrophy and regeneration did not show uniform change. In addition, there were differences in the ratio of increase among the stages of hypertrophy and regeneration. Therefore, consideration of the duration and method of physiotherapeutic intervention for atrophied muscle on the basis of the process of hypertrophy and regeneration is needed to provide more effective physiotherapy. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Thesis of Zushi, Kazumi / 都志 和美 博士学位論文(金沢大学 / 大学院医学系研究科) | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |