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門脈阻血に伴う多臓器うっ血の周術期における影響と多臓器相関
https://doi.org/10.24517/00051565
https://doi.org/10.24517/00051565186d912d-eaf0-435f-ae31-ad06136f6ab9
名前 / ファイル | ライセンス | アクション |
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ME-PR-HAYASHI-H-kaken 2016-4p.pdf (825.1 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2018-07-09 | |||||
タイトル | ||||||
タイトル | 門脈阻血に伴う多臓器うっ血の周術期における影響と多臓器相関 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Relationship between portal venous congestion and functions of splanchnic organs | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00051565 | |||||
ID登録タイプ | JaLC | |||||
著者 |
林, 泰寛
× 林, 泰寛 |
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著者別表示 |
Hayashi, Hironori
× Hayashi, Hironori |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||
書誌情報 |
平成27(2015)年度 科学研究費補助金 若手研究(B) 研究成果報告書 en : 2015 Fiscal Year Final Research Report 巻 2014-04-01 - 2016-03-31, p. 4p., 発行日 2016-05-16 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 肝胆膵・移植外科領域で頻発する門脈うっ血の影響とその軽減につき,ラットモデルにて研究を行った.門脈うっ血により,小腸粘膜を中心とした障害を受けるが,うっ血による前処置(congestive preconditioning; CPC)を行うことにより,障害は軽減,かつ生存率も有意に改善し,その有用性が示された.また, CPCによる抗アポトーシス経路の誘導が示唆された. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In clinical settings of hepato-pancreato-biliary and liver transplant surgery, portal venous congestion (PVC) is common pathophysiology. Therefore, effect and therapeutic approach for PVC was investigated by rat model. Intestinal mucosa was injured by PVC via apoptosis. By the induction of congestive preconditioning (CPC), intestinal mucosal injury and survival rate were significantly improved. The anti-apoptotic pathways was suspected to be involved in this availability, based on the result from immunohistochemical analysis. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:26861064, 研究期間(年度):2014-04-01 - 2016-03-31 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:研究課題「門脈阻血に伴う多臓器うっ血の周術期における影響と多臓器相関」課題番号26861064 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26861064/26861064seika/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=20543656 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=20543656 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26861064/ | |||||
関連名称 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26861064/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26861064/26861064seika/ | |||||
関連名称 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26861064/26861064seika/ |