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尿路HPV感染率と性器悪性腫瘍とHPVとの関連性についての検討
https://doi.org/10.24517/00054218
https://doi.org/10.24517/00054218a82fbc15-a3ce-488d-89ed-fe1a5538979c
名前 / ファイル | ライセンス | アクション |
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HO-PR-SHIGEHARA-K-kaken 2019-4p.pdf (82.9 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2020-04-17 | |||||
タイトル | ||||||
タイトル | 尿路HPV感染率と性器悪性腫瘍とHPVとの関連性についての検討 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Relationship between urinary HPV infection and urogenital tumor | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00054218 | |||||
ID登録タイプ | JaLC | |||||
著者別表示 |
Shigehara, Kazuyoshi
× Shigehara, Kazuyoshi |
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書誌情報 |
平成30(2018)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 en : 2018 Fiscal Year Final Research Report 巻 2016-04-01 - 2019-03-31, p. 4p., 発行日 2019-06-04 |
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出版者 | ||||||
出版者 | 金沢大学附属病院泌尿器科 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 泌尿器科を受診した患者845例を対象とし尿検体を用いて尿路HPV検出率を調査したところ、HPVおよび高リスク型HPV検出率はそれぞれ6.2%、3.1%であった。尿道炎患者、尿路悪性腫瘍患者においてHPV検出率が高いことが分かった。そこで尿路上皮癌患者に的を絞って膀胱洗浄液を用いてHPV検出率を調査したところ、HPV検出率は9.0%であった。 また、陰茎癌34例を用いてHPV検出率を検討したところ、HR-HPV検出率は35%であり、in situ hybridization(ISH)や免疫染色(IHC)にて、感染したHPVが発癌に関連していたことを確認した。 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The first study was conducted to examine HPV prevalence in urine samples as HPV screening of urinary tract in men. HPV and HR-HPV prevalence was 6.3 and 3.1%, respectively, among 845 urine samples from the patients who visited the urological clinic. HPV detection rates were significantly higher in the patients with urethritis or urogenital carcinoma. Therefore, we performed next study to investigate HPV prevalence in bladder wash samples from only patients with urinary bladder carcinoma. HPV detection rate was 9.0% in 67 nladderwash samples. Second, we investigated the relationship between HPV infection and penile carcinoma. HR-HPV was detected in 35% (12 cases) of penile carcinoma. In addition, in situ hybridization and immunohistochemistry could demonstrate that HPV infection certainly had an etiological role for the development of penile carcinoma. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:16K11040, 研究期間(年度):2016-04-01 - 2019-03-31 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:「尿路HPV感染率と性器悪性腫瘍とHPVとの関連性についての検討」研究成果報告書 課題番号16K11040 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-16K11040/16K11040seika/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=20595459 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=20595459 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K11040/ | |||||
関連名称 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K11040/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-16K11040/16K11040seika/ | |||||
関連名称 | https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-16K11040/16K11040seika/ |