Oral conditions may influence eating habits and nutrient intake, and nutrient intake in turn
may affect the gut microbiome. Furthermore, the microbiome can affect the health of the
host. However, few studies have addressed the above speculations. The present study was
performed to examine the relationships between oral conditions, nutrient intake, and the
gut microbiota in 239 participants in Ishikawa prefecture, Japan. Denture use altered the
dietary fiber intake and increased the relative abundance of Escherichia/Shigella in the gut.
However, several other oral conditions affected the gut microbiota without altering nutrient
intake. Diets high in dietary fiber have been reported to decrease the relative abundance
of Escherichia/Shigella. Therefore, this study suggested that denture use resulted in low
dietary fiber intake and increased the abundance of Escherichia/Shigella. As these bacteria
have been reported to cause inflammation in the colon and various diseases, the results
suggested that changes in oral conditions may lead to deterioration of several diseases.
Relationship between oral conditions and the gut microbiome in healthy adults in Ishikawa prefecture, Japan
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2434-1509_43-2-1-10.pdf
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