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Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma
https://doi.org/10.24517/00061732
https://doi.org/10.24517/000617320d707ec7-0606-4f8a-8906-9ce3a8de1bfa
名前 / ファイル | ライセンス | アクション |
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ME-PR-OHTA-T-19-3161.pdf (1.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-08-30 | |||||
タイトル | ||||||
タイトル | Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00061732 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Onishi, Ichiro
× Onishi, Ichiro× Kitagawa, Hirohisa× Harada, Kenichi× Maruzen, Syogo× Sakai, Seisyo× Makino, Isamu× Hayashi, Hironori× Nakagawara, Hisatoshi× Tajima, Hidehiro× Takamura, Hiroyuki× Fujimura, Takashi× Kayahara, Masato× Ikeda, Hiroko× Ohta, Tetsuo× Nakanuma, Yasuni |
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著者別名 |
北川, 裕久
× 北川, 裕久× 原田, 憲一× 牧野, 勇× 林, 泰寛× 中川原, 寿俊× 田島, 秀浩× 高村, 博之× 藤村, 隆× 萱原, 正都× 池田, 博子× 太田, 哲生× 中沼, 安二 |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||
書誌情報 |
World Journal of Gastroenterology 巻 19, 号 20, p. 3161-3164, 発行日 2013 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1007-9327 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12048247 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3748/wjg.v19.i20.3161 | |||||
出版者 | ||||||
出版者 | Baishideng Publishing Group Co | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We present the first case of an intraductal papillary neoplasm of the bile duct (IPNB) accompanying a mixed adenoneuroendocrine carcinoma (MANEC). A 74-yearold woman presented with fever of unknown cause. Laboratory data revealed jaundice and liver injury. Contrast-enhanced computed tomography revealed a 20 mm polypoid tumor in the dilated distal bile duct, which exhibited early enhancement and papillary growth. Upper gastrointestinal endoscopy revealed mucus production from the papilla of Vater, characterized by its protruding and dilated orifice. Endoscopic ultrasonography visualized the polypoid tumor in the distal bile duct, but no invasive region was suggested by diagnostic imaging. Therefore, the initial diagnosis was IPNB. After endoscopic nasobiliary drainage, a pylorus-preserving pancreaticoduodenectomy was performed. Pathological examination of the resected bile duct revealed papillary proliferation of biliary-type cells with nuclear atypia, indicating pancreaticobiliary-type IPNB. In addition, solid portions comprised of tumor cells with characteristic salt-and-pepper nuclei were evident. Immunohistochemistry revealed expression of the neuroendocrine marker synaptophysin in this solid component, diagnosing it as a neuroendocrine tumor (NET). Furthermore, the MIB-1 proliferation index of NET was higher than that of IPNB, and microinvasion of the NET component was found, indicating neuroendocrine carcinoma (NET G3). This unique case of MANEC, comprising IPNB and NET, provides insight into the pathogenesis of biliary NET. © 2013 Baishideng. All rights reserved. | |||||
権利 | ||||||
権利情報 | Copyright ©The Author(s). 2013 Published by Baishideng Publishing Group Inc. All rights reserved. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.wjgnet.com/ | |||||
関連名称 | https://www.wjgnet.com/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.wjgnet.com/1007-9327/index.htm | |||||
関連名称 | https://www.wjgnet.com/1007-9327/index.htm |