WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "af59d650-452e-445d-8922-dcf3217e3ba6"}, "_deposit": {"created_by": 18, "id": "58959", "owners": [18], "pid": {"revision_id": 0, "type": "depid", "value": "58959"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00058959", "sets": ["1875"]}, "author_link": ["43", "20080", "91488", "17754", "20737", "22446", "14708", "85011", "20090", "44095", "20341", "28557"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1985", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "363", "bibliographicPageStart": "359", "bibliographicVolumeNumber": "34", "bibliographic_titles": [{"bibliographic_title": "Radioisotopes"}]}]}, "item_4_creator_33": {"attribute_name": "著者別表示", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Mori, Hirofumi"}], "nameIdentifiers": [{"nameIdentifier": "20737", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "90019604", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90019604"}, {"nameIdentifier": "90019604", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000090019604"}]}, {"creatorNames": [{"creatorName": "Shiba, Kazuhiro"}], "nameIdentifiers": [{"nameIdentifier": "85011", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "40143929", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40143929"}]}, {"creatorNames": [{"creatorName": "Tsuji, Shiro"}], "nameIdentifiers": [{"nameIdentifier": "20090", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70227388", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000070227388"}]}, {"creatorNames": [{"creatorName": "Matsuda, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "17754", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "90173848", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90173848"}]}, {"creatorNames": [{"creatorName": "Hisada, Kinichi"}], "nameIdentifiers": [{"nameIdentifier": "20080", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "50019882", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=50019882"}]}, {"creatorNames": [{"creatorName": "Kojima, Kazuhiko"}], "nameIdentifiers": [{"nameIdentifier": "20341", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60019916", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60019916"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "ラット脳の3H-スピロペリドールによる受容体マクロオートラジオグラフィに関して, 基礎的検討, すなわちインキュベーション時間, 洗浄時間, 飽和実験, 作動薬, 拮抗薬による抑制効果について検討するとともに, ビデオカメラとコンピュータを組合せたVideo Digitizer Systemを用いてサブトラクションイメージを作成した。その結果, 本法はドーパミン等の受容体の形態学的分布ならびに動態の解析が可能であり, 神経精神疾患の病態解明ならびに陽電子, あるいは単光子横断断層イメージの解釈に有用と期待された。", "subitem_description_type": "Abstract"}, {"subitem_description": "The kinetic and pharmacological characteristics of 3H-spiroperidol binding sites were studied in slide mounted sections of rat forebrain, and optical binding conditions were defined. Using the receptor macroautoradiographic techniques with tritium-sensitive LKB sheet film, the distribution of dopamine (D2) receptor was determined in slices including striatum of rat brain. The autoradiograms were analyzed using Video Digitizer System combined with video camera and minicomputer, and the subtraction images were obtained.\nThese studies suggest that this quantitative receptor macroautoradiography might be useful in the explanation of etiology in the field of neuro psychiatric diseases and the fundamental studies of positron emission computed tomography, since this method has several advantages over in vivo autoradiography and in vitro receptor assay.", "subitem_description_type": "Abstract"}]}, "item_4_description_5": {"attribute_name": "提供者所属", "attribute_value_mlt": [{"subitem_description": "金沢大学疾患モデル総合研究センター", "subitem_description_type": "Other"}]}, "item_4_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.24517/00065221", "subitem_identifier_reg_type": "JaLC"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本アイソトープ協会 Japan Radioisotope Association"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3769/radioisotopes.34.7_359", "subitem_relation_type_select": "DOI"}}]}, "item_4_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "https://www.jstage.jst.go.jp/browse/radioisotopes/-char/ja/"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.jstage.jst.go.jp/browse/radioisotopes/-char/ja/", "subitem_relation_type_select": "URI"}}, {"subitem_relation_name": [{"subitem_relation_name_text": "http://www.jrias.or.jp/"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.jrias.or.jp/", "subitem_relation_type_select": "URI"}}]}, "item_4_rights_23": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright ©日本アイソトープ協会 Japan Radioisotope Association"}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00351589", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0033-8303", "subitem_source_identifier_type": "ISSN"}, {"subitem_source_identifier": "1884-4111", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "森, 厚文"}], "nameIdentifiers": [{"nameIdentifier": "91488", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "90019604", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90019604"}]}, {"creatorNames": [{"creatorName": "柴, 和弘"}], "nameIdentifiers": [{"nameIdentifier": "43", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "40143929", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40143929"}, {"nameIdentifier": "40143929", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=40143929"}, {"nameIdentifier": "40143929", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000040143929"}]}, {"creatorNames": [{"creatorName": "辻, 志郎"}], "nameIdentifiers": [{"nameIdentifier": "44095", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70227388", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70227388"}]}, {"creatorNames": [{"creatorName": "松田, 博史"}], "nameIdentifiers": [{"nameIdentifier": "22446", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "90173848", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=90173848"}, {"nameIdentifier": "90173848", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000090173848"}]}, {"creatorNames": [{"creatorName": "久田, 欣一"}], "nameIdentifiers": [{"nameIdentifier": "28557", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "50019882", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=50019882"}]}, {"creatorNames": [{"creatorName": "小島, 一彦"}], "nameIdentifiers": [{"nameIdentifier": "14708", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60019916", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000060019916"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2022-02-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-SHIBA-K-34_359.pdf", "filesize": [{"value": "1.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 1900000.0, "url": {"label": "ME-PR-SHIBA-K-34_359.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/58959/files/ME-PR-SHIBA-K-34_359.pdf"}, "version_id": "1530cd69-968d-4621-9a42-4420d467d47d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "receptor macroautoradiography", "subitem_subject_scheme": "Other"}, {"subitem_subject": "tritium-spiroperidol", "subitem_subject_scheme": "Other"}, {"subitem_subject": "brain", "subitem_subject_scheme": "Other"}, {"subitem_subject": "dopamine receptor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neuro-psychiatric diseases", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ"}, {"subitem_title": "Receptor macroautoradiography of 3H-spiroperidol binding in rat brain", "subitem_title_language": "en"}]}, "item_type_id": "4", "owner": "18", "path": ["1875"], "permalink_uri": "https://doi.org/10.24517/00065221", "pubdate": {"attribute_name": "公開日", "attribute_value": "2022-02-21"}, "publish_date": "2022-02-21", "publish_status": "0", "recid": "58959", "relation": {}, "relation_version_is_last": true, "title": ["ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ"], "weko_shared_id": -1}
ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ
https://doi.org/10.24517/00065221
https://doi.org/10.24517/000652212fa6710f-fb29-47a3-ba83-b74cf1af66dd
名前 / ファイル | ライセンス | アクション |
---|---|---|
ME-PR-SHIBA-K-34_359.pdf (1.9 MB)
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2022-02-21 | |||||
タイトル | ||||||
タイトル | ラット脳における3H-スピロペリドールによる受容体マクロオートラジオグラフィ | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Receptor macroautoradiography of 3H-spiroperidol binding in rat brain | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00065221 | |||||
ID登録タイプ | JaLC | |||||
著者 |
森, 厚文
× 森, 厚文× 柴, 和弘× 辻, 志郎× 松田, 博史× 久田, 欣一× 小島, 一彦 |
|||||
著者別表示 |
Mori, Hirofumi
× Mori, Hirofumi× Shiba, Kazuhiro× Tsuji, Shiro× Matsuda, Hiroshi× Hisada, Kinichi× Kojima, Kazuhiko |
|||||
提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学疾患モデル総合研究センター | |||||
書誌情報 |
Radioisotopes 巻 34, 号 7, p. 359-363, 発行日 1985 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0033-8303 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1884-4111 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00351589 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3769/radioisotopes.34.7_359 | |||||
出版者 | ||||||
出版者 | 日本アイソトープ協会 Japan Radioisotope Association | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ラット脳の3H-スピロペリドールによる受容体マクロオートラジオグラフィに関して, 基礎的検討, すなわちインキュベーション時間, 洗浄時間, 飽和実験, 作動薬, 拮抗薬による抑制効果について検討するとともに, ビデオカメラとコンピュータを組合せたVideo Digitizer Systemを用いてサブトラクションイメージを作成した。その結果, 本法はドーパミン等の受容体の形態学的分布ならびに動態の解析が可能であり, 神経精神疾患の病態解明ならびに陽電子, あるいは単光子横断断層イメージの解釈に有用と期待された。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The kinetic and pharmacological characteristics of 3H-spiroperidol binding sites were studied in slide mounted sections of rat forebrain, and optical binding conditions were defined. Using the receptor macroautoradiographic techniques with tritium-sensitive LKB sheet film, the distribution of dopamine (D2) receptor was determined in slices including striatum of rat brain. The autoradiograms were analyzed using Video Digitizer System combined with video camera and minicomputer, and the subtraction images were obtained. These studies suggest that this quantitative receptor macroautoradiography might be useful in the explanation of etiology in the field of neuro psychiatric diseases and the fundamental studies of positron emission computed tomography, since this method has several advantages over in vivo autoradiography and in vitro receptor assay. |
|||||
権利 | ||||||
権利情報 | Copyright ©日本アイソトープ協会 Japan Radioisotope Association | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/radioisotopes/-char/ja/ | |||||
関連名称 | https://www.jstage.jst.go.jp/browse/radioisotopes/-char/ja/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.jrias.or.jp/ | |||||
関連名称 | http://www.jrias.or.jp/ |