WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "ae017e5c-28ce-4b2f-bded-3096cf7301f3"}, "_deposit": {"created_by": 3, "id": "13526", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "13526"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00013526", "sets": ["1134"]}, "author_link": ["22063"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-07-15", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "518", "bibliographicPageStart": "509", "bibliographicVolumeNumber": "29", "bibliographic_titles": [{"bibliographic_title": "日本臨床麻酔学会誌 = The Journal of Japan Society for Clinical Anesthesia"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "ロピバカイン (商品名: アナペイン®) は光学異性体の研究によってもたらされた長時間作用性の局所麻酔薬 (局麻薬) であり, 特に高濃度溶液を使用すると, ブピバカインと同等の麻酔効果と作用時間をもたらす. 分離麻酔効果についてはブピバカインと差を認めないとの臨床報告が多く, ロピバカインの利点とはいえない. ブピバカインと比較してロピバカインが明らかに優れているのは, 心毒性が低いことである. したがって投与量が多くなるときや持続注入が必要なとき (区域ブロックや持続硬膜外鎮痛) に適する. ロピバカインはこれまでに開発された長時間作用性局麻薬のなかで, 最も安全域が広い薬物と考えられる. Ropivacaine is a new long-acting local anesthetic produced through modern technology to separate pure isomers. Although ropivacaine is supposed to have better differentiation in sensory/motor blockade, clinical studies do not necessarily support the differential effect. The relevant advantage of ropivacaine over racemic bupivacaine is reduced potential for systemic toxicity. Its better cardiotoxic profile is an especially important advantage when using techniques with a potential for high plasma concentrations.", "subitem_description_type": "Abstract"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本臨床麻酔学会 = The Japan Society for Clinical Anesthesia"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.2199/jjsca.29.509", "subitem_relation_type_select": "DOI"}}]}, "item_4_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.jstage.jst.go.jp/browse/jjsca/-char/ja/", "subitem_relation_type_select": "URI"}}, {"subitem_relation_type_id": {"subitem_relation_type_id_text": "http://jsca.umin.jp/", "subitem_relation_type_select": "URI"}}, {"subitem_relation_type_id": {"subitem_relation_type_id_text": "http://ci.nii.ac.jp/naid/10025382900/", "subitem_relation_type_select": "URI"}}]}, "item_4_rights_23": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright© The Japan Society for Clinical Anesthesia"}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00330159", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0285-4945", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "山本, 健"}], "nameIdentifiers": [{"nameIdentifier": "22063", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60135085", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000060135085"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-YAMAMOTO-K-509.pdf", "filesize": [{"value": "466.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 466400.0, "url": {"label": "ME-PR-YAMAMOTO-K-509.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/13526/files/ME-PR-YAMAMOTO-K-509.pdf"}, "version_id": "4e854251-b91f-4d1f-8649-81dadcb43985"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "ロピバカイン", "subitem_subject_scheme": "Other"}, {"subitem_subject": "局所麻酔薬", "subitem_subject_scheme": "Other"}, {"subitem_subject": "立体異性体", "subitem_subject_scheme": "Other"}, {"subitem_subject": "相対力価", "subitem_subject_scheme": "Other"}, {"subitem_subject": "心毒性", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Ropivacaine", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Local anesthetic", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Stereoisomer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Relative potency", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cardiotoxicity", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "ロピバカインの薬理学的特徴", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "ロピバカインの薬理学的特徴"}, {"subitem_title": "Basic and Clinical Pharmacology of Ropivacaine", "subitem_title_language": "en"}]}, "item_type_id": "4", "owner": "3", "path": ["1134"], "permalink_uri": "http://hdl.handle.net/2297/36361", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-03"}, "publish_date": "2017-10-03", "publish_status": "0", "recid": "13526", "relation": {}, "relation_version_is_last": true, "title": ["ロピバカインの薬理学的特徴"], "weko_shared_id": -1}
ロピバカインの薬理学的特徴
http://hdl.handle.net/2297/36361
http://hdl.handle.net/2297/363614585ce13-7e32-48ae-917c-a9843af47ba5
名前 / ファイル | ライセンス | アクション |
---|---|---|
ME-PR-YAMAMOTO-K-509.pdf (466.4 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | ロピバカインの薬理学的特徴 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Basic and Clinical Pharmacology of Ropivacaine | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
山本, 健
× 山本, 健 |
|||||
書誌情報 |
日本臨床麻酔学会誌 = The Journal of Japan Society for Clinical Anesthesia 巻 29, 号 4, p. 509-518, 発行日 2009-07-15 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0285-4945 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00330159 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2199/jjsca.29.509 | |||||
出版者 | ||||||
出版者 | 日本臨床麻酔学会 = The Japan Society for Clinical Anesthesia | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ロピバカイン (商品名: アナペイン®) は光学異性体の研究によってもたらされた長時間作用性の局所麻酔薬 (局麻薬) であり, 特に高濃度溶液を使用すると, ブピバカインと同等の麻酔効果と作用時間をもたらす. 分離麻酔効果についてはブピバカインと差を認めないとの臨床報告が多く, ロピバカインの利点とはいえない. ブピバカインと比較してロピバカインが明らかに優れているのは, 心毒性が低いことである. したがって投与量が多くなるときや持続注入が必要なとき (区域ブロックや持続硬膜外鎮痛) に適する. ロピバカインはこれまでに開発された長時間作用性局麻薬のなかで, 最も安全域が広い薬物と考えられる. Ropivacaine is a new long-acting local anesthetic produced through modern technology to separate pure isomers. Although ropivacaine is supposed to have better differentiation in sensory/motor blockade, clinical studies do not necessarily support the differential effect. The relevant advantage of ropivacaine over racemic bupivacaine is reduced potential for systemic toxicity. Its better cardiotoxic profile is an especially important advantage when using techniques with a potential for high plasma concentrations. | |||||
権利 | ||||||
権利情報 | Copyright© The Japan Society for Clinical Anesthesia | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/jjsca/-char/ja/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://jsca.umin.jp/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/10025382900/ |