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Treatment of primary central nervous system lymphoma with induction of complement-dependent cytotoxicity by intraventricular administration of autologous-serum-supplemented rituximab
http://hdl.handle.net/2297/45915
http://hdl.handle.net/2297/45915f522b3a6-8a54-4f98-a62d-de8e1ac40dd4
名前 / ファイル | ライセンス | アクション |
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ME-PR-NAKAO-S-80.pdf (189.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Treatment of primary central nervous system lymphoma with induction of complement-dependent cytotoxicity by intraventricular administration of autologous-serum-supplemented rituximab | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takami, Akiyoshi
× Takami, Akiyoshi× Hayashi, Akiyoshi× Kita, Daisuke× Nishimura, Ryosei× Asakura, Hidesaku× Nakao, Shinji |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 医薬保健研究域医学系 | |||||
書誌情報 |
Cancer Science 巻 97, 号 1, p. 80-83, 発行日 2006-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1347-9032 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11808050 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1111/j.1349-7006.2006.00138.x | |||||
出版者 | ||||||
出版者 | Japanese Cancer Association / Blackwell Publishing Ltd | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We describe an immunocompetent 19-year-old man with CD20-positive primary central nervous system (CNS) lymphoma refractory to chemotherapy and irradiation. After intraventricular administration of rituximab, a chimeric anti-CD20 monoclonal antibody, supplemented with autologous serum, a remarkable response developed to the CNS parenchymal lymphoma. Cytotoxicity assays showed that untreated patient's serum with rituximab, but not that of heat-inactivated patient's serum with rituximab or rituximab alone, induced potent rituximab-mediated cytotoxicity against tumor cells in the patient's cerebrospinal fluid, suggesting induction of complement-dependent cytotoxicity against CNS lymphoma. © 2006 Japanese Cancer Association. | |||||
権利 | ||||||
権利情報 | © Japanese Cancer Association 日本癌学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.jca.gr.jp/ |