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Development of immunotherapy for hepatocellular carcinoma
http://hdl.handle.net/2297/43915
http://hdl.handle.net/2297/43915c77c8c9a-8bda-4417-bfbe-d841d5a928e3
名前 / ファイル | ライセンス | アクション |
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ME-PR-KANEKO-S-123.pdf (100.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Development of immunotherapy for hepatocellular carcinoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Mizukoshi, Eishiro
× Mizukoshi, Eishiro× Kaneko, Shuichi |
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書誌情報 |
Inflammation and Immunity in Cancer p. 123-132, 発行日 2015-01-01 |
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ISBN | ||||||
識別子タイプ | ISBN | |||||
関連識別子 | 978-443155327-4 | |||||
ISBN | ||||||
識別子タイプ | ISBN | |||||
関連識別子 | 978-443155326-7 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/978-4-431-55327-4_10 | |||||
出版者 | ||||||
出版者 | Springer Japan | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Hepatocellular carcinoma (HCC) is the sixth most common type of cancer globally. Although many different kinds of treatment are performed for HCC according to the practical guidelines, the prognosis of patients is not still satisfactory because the effects of treatments are limited for advanced tumors and the recurrence rate of HCC, even in early stages, is very high. Therefore, immunotherapy is highly anticipated as a new treatment method for HCC. For the development of a new HCC therapy, we attempted to establish immunotherapy using dendritic cells (DCs) and peptide vaccine. In several clinical trials that we performed, we confirmed that the immunotherapy was safe and well-tolerated by HCC patients. We observed that DC therapy prolonged the recurrence-free survival of patients compared with that of patients without DC infusion, as well as observing the radiological anti-tumor effect in HCC patients with peptide vaccine. In this chapter, we summarize the results of previous studies using DC and peptide vaccine, including our own data, and describe the prospects of immunotherapy for HCC. © 2015, Springer Japan. All rights reserved. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | [Book Chapter] | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |