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Impact of visceral adipose tissue and subcutaneous adipose tissue on insulin resistance in middle-aged Japanese
https://doi.org/10.24517/00014454
https://doi.org/10.24517/00014454fc8c7516-506d-45a6-8fd8-f9c7a6c035d3
名前 / ファイル | ライセンス | アクション |
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ME-PR-YAMAGISHI-M-814.pdf (777.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-05-10 | |||||
タイトル | ||||||
タイトル | Impact of visceral adipose tissue and subcutaneous adipose tissue on insulin resistance in middle-aged Japanese | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00014454 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Oka, Rie
× Oka, Rie× Yagi, Kunimasa× Sakurai, Masaru× Nakamura, Koshi× Nagasawa, Shin-ya× Miyamoto, Susumu× Nohara, Atsushi× Kawashiri, Masa-aki× Hayashi, Kenshi× Takeda, Yoshiyu× Yamagishi, Masakazu |
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著者別表示 |
八木, 邦公
× 八木, 邦公× 櫻井, 勝× 中村, 幸志× 野原, 淳× 川尻, 剛照× 林, 研至× 武田, 仁勇× 山岸, 正和 |
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書誌情報 |
Journal of Atherosclerosis and Thrombosis 巻 19, 号 9, p. 814-822, 発行日 2012-09-24 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1340-3478 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11018976 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.5551/jat.12294 | |||||
出版者 | ||||||
出版者 | Japan Atherosclerosis Society = 日本動脈硬化学会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Aim: The enlargement of visceral adipose tissue (VAT) is considered to mediate the close relationship between obesity and insulin resistance. We aimed to determine whether a stronger association of VAT compared to subcutaneous adipose tissue (SAT) with insulin resistance could be confirmed and generalized in non-diabetic Japanese men and women. Methods: Participants were 912 non-diabetic Japanese (636 men and 276 women, mean age 52.4±7.0 years, and mean BMI 24.9±3.1 kg/m2). VAT and SAT were measured through the use of computed tomography scanning. Homeostatic model for the assessment of insulin resistance (HOMA-IR) and Matsuda insulin sensitivity index (ISI) were calculated based on results from the oral glucose tolerance test. Results: For both genders, subjects in higher tertiles of SAT as well as VAT showed significantly higher levels of HOMA-IR and lower levels of Matsuda ISI (p<0.001). In multiple regression analyses with VAT and SAT included in the model, only VAT, but not SAT, was independently associated with Matsuda ISI in women (p<0.001), whereas both SAT and VAT were independently associated with HOMA-IR and with Matsuda ISI in men (p<0.001). When VAT and waist circumference were jointly included in the model, only VAT, but not waist circumference, was independently associated with Matsuda ISI in women (p<0.001) but not in men. Conclusion: VAT had a stronger association with insulin resistance than SAT or waist circumference in women but not in men. BMI showed a comparable association with insulin resistance to VAT in this population. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出版者照会後に全文公開 | |||||
権利 | ||||||
権利情報 | Copyright © Japan Atherosclerosis Society 日本動脈硬化学会 (CC-BY NC SA) | 本論文の著作権は日本動脈硬化学会が保持しています | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/jat | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.j-athero.org/en/index.html |