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Circadian characteristics of mice depleted with GPR7
http://hdl.handle.net/2297/21282
http://hdl.handle.net/2297/21282f0d6471e-8e83-436c-8ad8-4121a3ff0429
名前 / ファイル | ライセンス | アクション |
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ME-PR-SAKURAI-T-357.pdf (560.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Circadian characteristics of mice depleted with GPR7 | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Uchio, Naohiro
× Uchio, Naohiro× Doi, Masao× Matsuo, Masahiro× Yamazaki, Fumiyoshi× Mizoro, Yasutaka× Hondo, Mari× Sakurai, Takeshi× Okamura, Hitoshi |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||
書誌情報 |
Biomedical Research 巻 30, 号 6, p. 357-364, 発行日 2009-12-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0388-6107 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00110128 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2220/biomedres.30.357 | |||||
出版者 | ||||||
出版者 | Biomedical Research Press | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | GPR7, now known as a receptor of neuropeptide B and neuropeptide W, is expressed in neurons of the suprachiasmatic nucleus (SCN), the mammalian circadian center. By the quantitative in situ hybridization, we demonstrated that GPR7 mRNA showed a significant circadian rhythm in the SCN showing a peak at early subjective night in both light-dark and constant dark. We characterized the circadian feature of GPR7-knockout mice, but the period length and the phase-dependent phase shift to light exposure were not disordered in GPR7-knockout mice. Moreover, the food-anticipatory behavior in restricted feeding schedule was observed in this gene-deleted mouse similar to wild-type. These results indicate that the role of GPR7 may be subtle or limited in relation to the circadian clock despite its robust expression in the SCN. | |||||
権利 | ||||||
権利情報 | Copyright (c) 2010 Biomedical Research Press | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.jstage.jst.go.jp/article/biomedres/30/6/30_357/_article |