WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "f3b61581-a476-42b4-a0c3-03122ba5570d"}, "_deposit": {"created_by": 3, "id": "14763", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "14763"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00014763", "sets": ["1135"]}, "author_link": ["26389", "26390", "26391", "26369", "26388"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1987-07-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "2760", "bibliographicPageStart": "2755", "bibliographicVolumeNumber": "35", "bibliographic_titles": [{"bibliographic_title": "Chemical \u0026 pharmaceutical bulletin"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The synthesis of (±)-9-demethylprotoemetinol [(±)-3d] was accomplished by LiAlH_4 reduction of the tricyclic ester (±)-5 and subsequent debenzylation of the resulting tricyclic-alcohol (±)-10. Acetylation of (±)-3d with acetic anhydride and pyridine gave the diacetate (±)-11. The same sequence of reactions starting with (-)-5 afforded (-)-9-demethylprotoemetinol [(-)-3d] and the diacetate (-)-11 through (-)-10. Parallel synthetic routes starting with the isomeric tricyclic esters (±)-9 and (-)-9 produced (±)- and (-)-10-demethylprotoemetinols [(±)-4d and (-)-4d] and the corresponding diacetates [(±)-13 and (-)-13] through (±)-12 and (-)-12, respectively. The correctness of the structure and absolute stereochemistry of an Alangiutn alkaloid inferred to be 10-demethylprotoemetinol was confirmed by a direct comparison of its diacetate with synthetic (-)-13.", "subitem_description_type": "Abstract"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本薬学会"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1248/cpb.35.2755", "subitem_relation_type_select": "DOI"}}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00602100", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0009-2363", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Fujii, Tozo"}], "nameIdentifiers": [{"nameIdentifier": "26388", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohba, Masashi"}], "nameIdentifiers": [{"nameIdentifier": "26369", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60115219", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60115219"}, {"nameIdentifier": "60115219", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000060115219"}]}, {"creatorNames": [{"creatorName": "Ali, Esahak"}], "nameIdentifiers": [{"nameIdentifier": "26389", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Hitoshi"}], "nameIdentifiers": [{"nameIdentifier": "26390", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakaguchi, Jun"}], "nameIdentifiers": [{"nameIdentifier": "26391", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "PH-PR-OHBA-M-2755.pdf", "filesize": [{"value": "833.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 833000.0, "url": {"label": "PH-PR-OHBA-M-2755.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/14763/files/PH-PR-OHBA-M-2755.pdf"}, "version_id": "29405886-5266-4b33-96f1-92bd020362b6"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Alangium lamarckii alkaloid", "subitem_subject_scheme": "Other"}, {"subitem_subject": "demethylproloemetinol", "subitem_subject_scheme": "Other"}, {"subitem_subject": "racemic synthesis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "chiral synthesis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lithium aluminum hydride ester reduction", "subitem_subject_scheme": "Other"}, {"subitem_subject": "benzyl ether hydrogenolysis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "acetic anhydride-pyridine O-acetylation", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Quinolizidines. XX. Racetnic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol(Organic,Chemical)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Quinolizidines. XX. Racetnic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol(Organic,Chemical)"}]}, "item_type_id": "4", "owner": "3", "path": ["1135"], "permalink_uri": "http://hdl.handle.net/2297/7667", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-03"}, "publish_date": "2017-10-03", "publish_status": "0", "recid": "14763", "relation": {}, "relation_version_is_last": true, "title": ["Quinolizidines. XX. Racetnic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol(Organic,Chemical)"], "weko_shared_id": 3}
Quinolizidines. XX. Racetnic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol(Organic,Chemical)
http://hdl.handle.net/2297/7667
http://hdl.handle.net/2297/7667e05540d4-c691-4843-8adc-31bf44d2e49d
名前 / ファイル | ライセンス | アクション |
---|---|---|
PH-PR-OHBA-M-2755.pdf (833.0 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Quinolizidines. XX. Racetnic and Chiral Syntheses of the Alangium Alkaloids 9-Demethylprotoemetinol and 10-Demethylprotoemetinol(Organic,Chemical) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Fujii, Tozo
× Fujii, Tozo× Ohba, Masashi× Ali, Esahak× Suzuki, Hitoshi× Sakaguchi, Jun |
|||||
書誌情報 |
Chemical & pharmaceutical bulletin 巻 35, 号 7, p. 2755-2760, 発行日 1987-07-25 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0009-2363 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00602100 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/cpb.35.2755 | |||||
出版者 | ||||||
出版者 | 日本薬学会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The synthesis of (±)-9-demethylprotoemetinol [(±)-3d] was accomplished by LiAlH_4 reduction of the tricyclic ester (±)-5 and subsequent debenzylation of the resulting tricyclic-alcohol (±)-10. Acetylation of (±)-3d with acetic anhydride and pyridine gave the diacetate (±)-11. The same sequence of reactions starting with (-)-5 afforded (-)-9-demethylprotoemetinol [(-)-3d] and the diacetate (-)-11 through (-)-10. Parallel synthetic routes starting with the isomeric tricyclic esters (±)-9 and (-)-9 produced (±)- and (-)-10-demethylprotoemetinols [(±)-4d and (-)-4d] and the corresponding diacetates [(±)-13 and (-)-13] through (±)-12 and (-)-12, respectively. The correctness of the structure and absolute stereochemistry of an Alangiutn alkaloid inferred to be 10-demethylprotoemetinol was confirmed by a direct comparison of its diacetate with synthetic (-)-13. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |