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Technetium-99m-Tetrofosmin Uptakes on Dipyridamole-Stress Planar Imaging Comparison with Those in Excised Rat Organs
http://hdl.handle.net/2297/45917
http://hdl.handle.net/2297/459176fbee07c-11a3-4a0b-930a-9c21f3667b0d
名前 / ファイル | ライセンス | アクション |
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AA11137625-24-1-21-29.pdf (575.9 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-10-04 | |||||
タイトル | ||||||
タイトル | Technetium-99m-Tetrofosmin Uptakes on Dipyridamole-Stress Planar Imaging Comparison with Those in Excised Rat Organs | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 99mTc-tetrofosmin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Organ uptake | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Planar image | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Dipyridamole | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rat | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | ラットを用いたジピリダモール負荷プラナー画像における 99mTc-tetrofosmin 摂取率: 摘出臓器の摂取率との比較 | |||||
著者 |
Onoguchi, Masahisa
× Onoguchi, Masahisa× Takayama, Teruhiko× Tonami, Norihisa× Mizukami, Yuji× Kyogoku, Shinsuke× Naoi, Yutaka× Irimoto, Masahiro× Maehara, Tadayuki |
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書誌情報 |
金沢大学医学部保健学科紀要 巻 24, 号 1, p. 21-29, 発行日 2000-12-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1342-7318 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11137625 | |||||
出版者 | ||||||
出版者 | 金沢大学医学部保健学科 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We studied how precisely images reflect tracer uptake .in the myocardium, and examined what degree technetium-99m-tetrofosmin (c-tetrofosmin) in the liver and gastrointestine gave the effect to a myocardial image. After administering dipyridamole and 99m Tc tetrofosmin to normal rats, we compared the myocardial uptakes obtained using a gamma camera with the actual uptakes in the excised organs. Methods : Thirty-seven rats were used. Following imaging the anterior view at 5, 10, 15, 30, 60 and 90 min after admini stration of the tracer, uptakes in the heart, lung, liver and blood were estimated with a well-type scintillation counter (WC) and represented as percentage of the injected dose per gram of tissue (%ID/g). The regions of interest (ROis) were placed on planar images (PI) and the uptake in each organ was estimated as percentage of the injected dose per pixel (%ID/pixel). The ratios of PI-to-WC and heart-to-organ were also evaluated. Results : Cardiac uptake with WC was 1.688%± 0.395% at 10 min post-injection. On the other hand, that with PI was 1.855%±0.965% at 10 min post-injection. There were particularly great differences from 15 min post-injection between both measurements (PI/WC ratio : about 1.2 times). Pulmonary uptake with WC was the maximum at 15 min (0.861%± 0.387%) post-injection, and there was. hardly a variation in the activity later than 15 min. However, PI measurement showed the maximum value at 15 min (0.777%±0.163%), and decreased gradually. Hepatic uptake with WC was the maximum at 5 min (1.545%±0.563 %), and rapidly decreased. On the other hand, PI measurement showed higher value than WC as" the whole. Conclusion : Pl measurement showed higher uptakes in each organ than WC measurement. There were great differences between both measurements, at late phase particularly. As one of these causes, it was considered that the decrease of activity in blood was different from that in each organ with increasing time. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |