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IgG4-related skin lesions in a patient with IgG4-related chronic sclerosing dacryoadenitis and sialoadenitis
http://hdl.handle.net/2297/29196
http://hdl.handle.net/2297/29196c1dc3ede-6d0c-4c96-88bf-d340a09b3fa1
名前 / ファイル | ライセンス | アクション |
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HO-PR-KAWANO-M-1465.pdf (1.4 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | IgG4-related skin lesions in a patient with IgG4-related chronic sclerosing dacryoadenitis and sialoadenitis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kakuchi, Yasushi
× Kakuchi, Yasushi× Yamada, Kazunori× Suzuki, Yasunori× Ito, Naoko× Yagi, Kunimasa× Matsumura, Masami× Yamagishi, Masakazu× Umehara, Hisanori× Zen, Yoh× Hasegawa, Minoru× Takehara, Kazuhiko× Kawano, Mitsuhiro |
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書誌情報 |
Internal Medicine 巻 50, 号 14, p. 1465-1469, 発行日 2011-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0918-2918 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10827774 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2169/internalmedicine.50.5239 | |||||
出版者 | ||||||
出版者 | The Japanese Society of Internal Medicine | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We describe a 60-year-old man with IgG4-related chronic sclerosing dacryoadenitis and sialoadenitis associated with lymphoplasmacytic and eosinophilic infiltration in erythematous nodules. Physical examination revealed left eye extrusion and small itchy nodules on the scalp and neck. The serum IgG level was 1,570 mg/dL, IgG4 463 mg/dL (29.5%), and IgE 4,554 IU/mL. Lacrimal gland biopsy disclosed prominent infiltrates of IgG4-positive plasma cells and scattered eosinophilic infiltrates with fibrosis, consistent with IgG4-related disease. A skin biopsy of a cutaneous nodule demonstrated that the infiltrated plasma cells around arterioles or venules in the deep dermis and subcutaneous fat tissue were strongly positive for IgG4. Although the swollen lacrimal and parotid gland and itchy subcutaneous erythematous nodules improved rapidly with oral prednisolone at a dose of 20 mg per day, the skin, lacrimal, and parotid lesions deteriorated simultaneously during steroid tapering and improved after increasing the dosage. As skin lesions are easy to biopsy, further study of the skin manifestations of IgG4-related disease will be important in further clarifying the clinical spectrum, pathophysiology and response to therapy of this disorder. © 2011 The Japanese Society of Internal Medicine. | |||||
権利 | ||||||
権利情報 | Copyright (c) 2011 by The Japanese Society of Internal Medicine | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://japanlinkcenter.org/JST.JSTAGE/internalmedicine/50.5239 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.naika.or.jp/imonline/index.html |