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黄連解毒湯およびその構成生薬の心・血管系に対する作用 : ほてり・顔面紅潮に対する有効性の検討
http://hdl.handle.net/2297/23603
http://hdl.handle.net/2297/236039a9c0d6e-81f6-4e9b-945b-c85f3afc3acc
名前 / ファイル | ライセンス | アクション |
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PH-PR-MIAMOTO-K-230.pdf (866.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-05 | |||||
タイトル | ||||||
タイトル | 黄連解毒湯およびその構成生薬の心・血管系に対する作用 : ほてり・顔面紅潮に対する有効性の検討 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effects of Oren-gedoku-to and its constituents on the cardiovascular system : Investigation of its efficacy in hotflush | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
脇田, 広美
× 脇田, 広美× 宮本, 謙一 |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学附属病院薬剤部 | |||||
書誌情報 |
Journal of traditional medicines = 和漢医薬学雑誌 巻 19, 号 6, p. 230-237, 発行日 2002-12-20 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1880-1447 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12035198 | |||||
出版者 | ||||||
出版者 | Medical and Pharmaceutical Society for WAKAN-YAKU = 和漢医薬学会 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The auricular blood flow in intact rats decreased maximally at 15min after administration of Oren-gedoku-to extract (1.0/kg, intraduodenal (i.d.)), although the heart rates and the blood pressure scarcely changed. In rats pretreated intravenously with theophylline (5mg/kg), the auricular blood flow also decreased similarly after its administration, while the heart rate and the blood pressure decreased. The extract (0.35g/kg, i.d.) of Scutellariae Radix which is the main constituent of Oren-gedoku-to decreased the auricular blood flow, the heart rate, and the blood pressure. On the other hand, In rats pretreated with reserpine (5mg/kg, i.v.) 24hrs before the administration, the blood flow, heart rate and blood pressure were not hardly affected after administration of both Oren-gedoku-to and Scutellariae Radix. In the isolated right and left atria, and papillary muscle of rats, the frequency and the strength of contraction was not influenced with Oren-gedoku-to extract and its constituent plant extracts. In the isolated Langendorff's heart of rats, the left ventricular systolic maximum pressure and heart rate were not influenced with Oren-gedoku-to, although the coronary flow was slightly increased. The above results suggest that Oren-gedoku-to is useful in hotflush, because of its decreasing effects on auricular blood flow without cardiac function, and among the constituent plants of Oren-gedoku-to, Scutellariae Radix plays a main part. | |||||
権利 | ||||||
権利情報 | 本文データは和漢医薬学会の許諾に基づきCiNiiから複製したものである | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.wakan-iyaku.gr.jp/index2.html | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/110001846576/en/ |