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難治性慢性咳嗽の克服に向けて: 咳嗽発生メカニズムの機序解明と治療法の開発
https://doi.org/10.24517/00050067
https://doi.org/10.24517/00050067e787739a-b31a-4961-98a6-814ac2a0edac
名前 / ファイル | ライセンス | アクション |
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ME-PR-FUJIMURA-M-kaken 2011-6p.pdf (273.5 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2018-02-08 | |||||
タイトル | ||||||
タイトル | 難治性慢性咳嗽の克服に向けて: 咳嗽発生メカニズムの機序解明と治療法の開発 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | To overcome intractable chronic cough: mechanism of cough and development of therapy | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00050067 | |||||
ID登録タイプ | JaLC | |||||
著者別表示 |
Fujimura, Masaki
× Fujimura, Masaki |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||
書誌情報 |
平成22(2010)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 en : 2010 Fiscal Year Final Research Report 巻 2008-2010, p. 6p., 発行日 2011-05-10 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 咳嗽反応の末梢機序には少なくとも以下の2つ経路が存在することが明らかとなった。(1)気道表層の気管支上皮間や上皮下に存在する知覚神経終末(咳受容体)の感受性亢進(アトピー咳嗽)あるいは過剰刺激による咳嗽反応(副鼻腔気管支症候群)、(2)気管支壁深層の平滑筋層の中または周囲に存在する知覚神経終末(Aδ線維)の平滑筋収縮に対する過剰反応(咳喘息)、あるいは過剰な平滑筋収縮による過刺激(気管支喘息)。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | It has been disclosed that there are at least two pathway of cough reflex : (1) increased cough receptor sensitivity (atopic cough) or hyper-stimulation to cough receptors (sinobronchial syndrome) which are present in inter- and sub epithelium of airway, (2) increased response of sensory nerve endings (Adelta-fibers) in intra- and peri-smooth muscle layer to the smooth muscle contraction (cough variant asthma) or hyper-stimulation (strong smooth muscle contraction) to the nerve endings. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:20590916, 研究期間(年度):2008-2010 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:研究課題「難治性慢性咳嗽の克服に向けて: 咳嗽発生メカニズムの機序解明と治療法の開発」課題番号20590916 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20590916/20590916seika/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=90190066 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=90190066 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20590916/ | |||||
関連名称 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20590916/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20590916/20590916seika/ | |||||
関連名称 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20590916/20590916seika/ |