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分子分類を利用した腸管寄生原虫の網羅的検出法の開発
https://doi.org/10.24517/00051092
https://doi.org/10.24517/00051092df353854-c60d-439d-86ad-3ee9a5647e56
名前 / ファイル | ライセンス | アクション |
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ME-PR-TOKORO-S-kaken 2016-4p.pdf (91.2 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2018-06-18 | |||||
タイトル | ||||||
タイトル | 分子分類を利用した腸管寄生原虫の網羅的検出法の開発 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Development of comprehensive detection methods of protozoan parasites using molecular taxonomy | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00051092 | |||||
ID登録タイプ | JaLC | |||||
著者 |
所, 正治
× 所, 正治 |
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著者別表示 |
Tokoro, Masaharu
× Tokoro, Masaharu |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学先進予防医学研究センター | |||||
書誌情報 |
平成27(2015)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 en : 2015 Fiscal Year Final Research Report 巻 2013-04-01 - 2016-03-31, p. 4p., 発行日 2016-06-14 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 寄生原虫の精製DNAをターゲットに各種原虫を特異的に検出可能な網羅的PCRスクリーニング法を開発し、以下の研究成果を達成した。(1)ケニアのHIV感染学童のEntamoeba属感染状況の分子疫学調査:健常児との比較においてHIV感染学童におけるアメーバ類感染の低下をみた。(2)非病原性とされてきたポレックアメーバが豚下痢症において病原性を示す可能性を提示。(3)トリコモナス属の分子疫学的調査:腸トリコモナスの人獣共通感染についてエビデンスを提示した。(4)その他、ジアルジア症、アメーバ性肝膿瘍の診断・報告、野鼠に分布するTrypanosoma属を分子同定によりT. grosiと同定。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A systemic screening method targeting protozoan parasites was developed, and applied the methods to various clinical examinations and molecular epidemiologic investigations. The achieved results are; (1) Lower prevalence of Entamoeba species in children with vertically transmitted HIV infection were observed in Western Kenya. (2) The genetic identification of Entamoeba polecki was confirmed from pigs in Japan and revealed its potential pathogenic role in the ulcerative colitis. (3) Genetic identification of various trichomonads species isolated from humans and related mammals were confirmed. The data showed the wide distribution of an specific genotype of Pentatrichomonas hominis among human and animals, and thus P. hominis is considered to be a zoonotic protozoan. (4) Other achievements; Clinical diagnoses of giardiasis and amebic liver access. The molecular epidemiologic investigation of Trypanosoma sp. among Japanese wild rodents could reveal the presence of T. grosi. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:25460514, 研究期間(年度):2013-04-01 - 2016-03-31 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:研究課題「分子分類を利用した腸管寄生原虫の網羅的検出法の開発」課題番号25460514 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25460514/25460514seika/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=30338024 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=30338024 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25460514/ | |||||
関連名称 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25460514/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25460514/25460514seika/ | |||||
関連名称 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-25460514/25460514seika/ |