WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "45619ab3-c049-4f40-a8a0-ec0e34301480"}, "_deposit": {"created_by": 18, "id": "49347", "owners": [18], "pid": {"revision_id": 0, "type": "depid", "value": "49347"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00049347", "sets": ["1134"]}, "author_link": ["45834", "73997", "413", "88635", "568", "88633"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-09-23", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageStart": "38p.", "bibliographicVolumeNumber": "11", "bibliographic_titles": [{"bibliographic_title": "Nutrients"}]}]}, "item_4_creator_33": {"attribute_name": "著者別表示", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "長田, 直人"}], "nameIdentifiers": [{"nameIdentifier": "568", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70456408", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=70456408"}, {"nameIdentifier": "70456408", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000070456408"}]}, {"creatorNames": [{"creatorName": "太田, 嗣人"}], "nameIdentifiers": [{"nameIdentifier": "413", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60397213", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60397213"}, {"nameIdentifier": "60397213", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=60397213"}, {"nameIdentifier": "60397213", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000060397213"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Metabolic endotoxemia is a condition in which blood lipopolysaccharide (LPS) levels are elevated, regardless of the presence of obvious infection. It has been suggested to lead to chronic inflammation-related diseases such as obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), pancreatitis, amyotrophic lateral sclerosis, and Alzheimer\u0027s disease. In addition, it has attracted attention as a target for the prevention and treatment of these chronic diseases. As metabolic endotoxemia was first reported in mice that were fed a high-fat diet, research regarding its relationship with diets has been actively conducted in humans and animals. In this review, we summarize the relationship between fat intake and induction of metabolic endotoxemia, focusing on gut dysbiosis and the influx, kinetics, and metabolism of LPS. We also summarize the recent findings about dietary factors that attenuate metabolic endotoxemia, focusing on the regulation of gut microbiota. We hope that in the future, control of metabolic endotoxemia using dietary factors will help maintain human health.", "subitem_description_type": "Abstract"}]}, "item_4_description_5": {"attribute_name": "提供者所属", "attribute_value_mlt": [{"subitem_description": "金沢大学医学系細胞分子機能学", "subitem_description_type": "Other"}]}, "item_4_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.24517/00055660", "subitem_identifier_reg_type": "JaLC"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Multidisciplinary Digital Publishing Institute (MDPI)"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3390/nu11102277", "subitem_relation_type_select": "DOI"}}]}, "item_4_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "https://www.mdpi.com/2072-6643/11/10/2277"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.mdpi.com/2072-6643/11/10/2277", "subitem_relation_type_select": "URI"}}, {"subitem_relation_name": [{"subitem_relation_name_text": "https://www.mdpi.com/journal/nutrients"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.mdpi.com/journal/nutrients", "subitem_relation_type_select": "URI"}}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2072-6643", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Fuke, Nobuo"}], "nameIdentifiers": [{"nameIdentifier": "88633", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagata, Naoto"}], "nameIdentifiers": [{"nameIdentifier": "45834", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70456408", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70456408"}]}, {"creatorNames": [{"creatorName": "Suganuma, Hiroyuki"}], "nameIdentifiers": [{"nameIdentifier": "88635", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ota, Tsuguhito"}], "nameIdentifiers": [{"nameIdentifier": "73997", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60397213", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60397213"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-NAGATA-N-11-02277.pdf", "filesize": [{"value": "962.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 962800.0, "url": {"label": "ME-PR-NAGATA-N-11-02277.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/49347/files/ME-PR-NAGATA-N-11-02277.pdf"}, "version_id": "51e2c681-99cd-4d62-80e9-036bea51947e"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "dietary factors", "subitem_subject_scheme": "Other"}, {"subitem_subject": "gut microbiota", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lipopolysaccharide", "subitem_subject_scheme": "Other"}, {"subitem_subject": "metabolic endotoxemia", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors"}]}, "item_type_id": "4", "owner": "18", "path": ["1134"], "permalink_uri": "https://doi.org/10.24517/00055660", "pubdate": {"attribute_name": "公開日", "attribute_value": "2019-10-03"}, "publish_date": "2019-10-03", "publish_status": "0", "recid": "49347", "relation": {}, "relation_version_is_last": true, "title": ["Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors"], "weko_shared_id": 18}
Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors
https://doi.org/10.24517/00055660
https://doi.org/10.24517/000556600ea54211-840c-4c12-8518-91deef9526cf
名前 / ファイル | ライセンス | アクション |
---|---|---|
ME-PR-NAGATA-N-11-02277.pdf (962.8 kB)
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2019-10-03 | |||||
タイトル | ||||||
タイトル | Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00055660 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Fuke, Nobuo
× Fuke, Nobuo× Nagata, Naoto× Suganuma, Hiroyuki× Ota, Tsuguhito |
|||||
著者別表示 |
長田, 直人
× 長田, 直人× 太田, 嗣人 |
|||||
提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医学系細胞分子機能学 | |||||
書誌情報 |
Nutrients 巻 11, 号 10, p. 38p., 発行日 2019-09-23 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2072-6643 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/nu11102277 | |||||
出版者 | ||||||
出版者 | Multidisciplinary Digital Publishing Institute (MDPI) | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Metabolic endotoxemia is a condition in which blood lipopolysaccharide (LPS) levels are elevated, regardless of the presence of obvious infection. It has been suggested to lead to chronic inflammation-related diseases such as obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), pancreatitis, amyotrophic lateral sclerosis, and Alzheimer's disease. In addition, it has attracted attention as a target for the prevention and treatment of these chronic diseases. As metabolic endotoxemia was first reported in mice that were fed a high-fat diet, research regarding its relationship with diets has been actively conducted in humans and animals. In this review, we summarize the relationship between fat intake and induction of metabolic endotoxemia, focusing on gut dysbiosis and the influx, kinetics, and metabolism of LPS. We also summarize the recent findings about dietary factors that attenuate metabolic endotoxemia, focusing on the regulation of gut microbiota. We hope that in the future, control of metabolic endotoxemia using dietary factors will help maintain human health. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.mdpi.com/2072-6643/11/10/2277 | |||||
関連名称 | https://www.mdpi.com/2072-6643/11/10/2277 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.mdpi.com/journal/nutrients | |||||
関連名称 | https://www.mdpi.com/journal/nutrients |