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脊椎全摘術後の再建に関する生体力学的検討
https://doi.org/10.24517/00056906
https://doi.org/10.24517/00056906948efc3d-db50-44c3-9227-1abcb5efea52
名前 / ファイル | ライセンス | アクション |
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ME-PR-KAWAHARA-N-kaken 2003-2p.pdf (76.0 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2022-04-25 | |||||
タイトル | ||||||
タイトル | 脊椎全摘術後の再建に関する生体力学的検討 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Biomechanical analysis of the reconstruction method following total spondylectomy | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00056906 | |||||
ID登録タイプ | JaLC | |||||
著者 |
川原, 範夫
× 川原, 範夫 |
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著者別表示 |
Kawahara, Norio
× Kawahara, Norio |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||
書誌情報 |
平成13(2001)年度 科学研究費補助金 基盤研究(C) 研究成果報告書概要 en : 2001 Fiscal Year Final Research Report Summary 巻 2000-2001, p. 2p., 発行日 2003-09-16 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 脊椎悪性腫瘍に対する脊椎全摘術は腫瘍椎骨を周囲の靭帯組織を含めて切除するため、脊柱の支持性は完全に失われる一方で、術後長期生存が見込まれる患者に対してのみ適応があり、その脊柱再建は重要な問題である。理想的な椎体間の骨性癒合を得ることを目的として、内部に移植骨を充填したtitanium cageを椎体再建に用いている。i)後方pedicle screw & rodのみの固定、ii)後方+前方instrumentation(Kaneda SRなど)による固定、の両者が臨床で行われており、後者のほうが力学強度に優れるとする報告がある。しかしtitamum cage内の移植骨のremodelingにとっては適度の力学ストレスが加わることが必須であり、強固な支持性を持ったtitanium cage内部の移植骨の力学的環境を検討した報告はない。それぞれの再建方法のヒト屍体脊椎標本を用いた力学試験と有限要素モデルを作製し解析比較した本研究では、脊椎全摘後再建において、後方pedicle screw & rodに前方instrumentationを追加することによって、後方instrumentationにかかる負担は軽減できるものの、cage内の移植骨に加わる応力は著しく減少することが明らかとなった。後方instrumentationのみで再建する方法はtitanium cageに対するstress shieldingが小さく骨のremodelingに有利である可能性がある。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Only a few studies have investigated the biomechanical properties of the reconstruction method following total spondylectomy for spinal malignant tumors. Biological bony fusion is required for the maintenance of spinal stability in patients with long-term life expectancy. The most recent reconstruction techniques include a titanium mesh cage filled with autologous bone as an anterior strut. The need of additional anterior instrumentation with posterior pedicle screws and rods in the reconstruction following total spondylectomy is controversial. It has been well defined, in previous studies, that biomechanical stress is necessary for bone remodeling and fusion. Therefore transmission of mechanical stress to the grafted bone inside the titanium mesh cage must be an important factor for fusion and remodeling. No published reports comparing the load-sharing properties of the different reconstruction methods fllowing total spondylectomy exist. The purpose of this finite element analysis was to compare the effect of two reconstruction methods, posterior instrumentation versus anterior/posterior instrumentation, on load sharing through a titanium mesh cage following total spondylectomy. This experiment shows that from the viewpoint of stress-shielding, the reconstruction method using additional anterior instrumentation with posterior pedicle screws, stress shields the titanium cage to a greater degree than does the system using posterior prdicle screw fixation alone. A reconstruction method with no anterior fixation should provide adequate stress for remodeling of the bone graft inside the titanium mesh cages. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:12671402, 研究期間(年度):2000-2001 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:研究課題「脊椎全摘術後の再建に関する生体力学的検討」課題番号12671402 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-12671402/126714022001kenkyu_seika_hokoku_gaiyo/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=70214674 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=70214674 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671402/ | |||||
関連名称 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671402/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-12671402/126714022001kenkyu_seika_hokoku_gaiyo/ | |||||
関連名称 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-12671402/126714022001kenkyu_seika_hokoku_gaiyo/ |