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大気粉塵中遷移金属による喘息患者の症状悪化機構の解明
https://doi.org/10.24517/00057984
https://doi.org/10.24517/000579847f0d339b-a643-4be7-8348-7752ca18c72d
名前 / ファイル | ライセンス | アクション |
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SC-PR-MICHIGAMI-Y-kaken 2020-6p.pdf (322.9 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2021-04-26 | |||||
タイトル | ||||||
タイトル | 大気粉塵中遷移金属による喘息患者の症状悪化機構の解明 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Elucidation of mechanism for exacerabting symptoms of asthma patients by metals contained in ambient dust | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00057984 | |||||
ID登録タイプ | JaLC | |||||
著者 |
道上, 義正
× 道上, 義正 |
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著者別表示 |
Michigami, Yoshimasa
× Michigami, Yoshimasa |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学環境保全センター | |||||
書誌情報 |
令和1(2019)年度 科学研究費補助金 基盤研究(C) 研究成果報告書 en : 2019 Fiscal Year Final Research Report 巻 2017-04-01 - 2020-03-31, p. 6p., 発行日 2020-06-10 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 慢性咳嗽患者の血液を用いた好塩基球活性化試験の条件を決めた。この条件で気管支喘息患者のスギ花粉抗原による好塩基球活性化を多環芳香族炭化水素類でさらに活性化できることを確認できた。一方、重金属の効果は確認することができなかった。大気粉塵(総浮遊粒子状物質と微小粒子状物質(PM2.5))の粒径の違いで構成成分(多環芳香族炭化水素類と重金属)が異なることが確認できた。また、季節変動も確認できた。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The condition to conduct basophil activation test with chronic cough patients were determined. Using this condition, more activation of basophil activated by cedar pollen antigen by polycyclic aromatic hydrocarbon could be confirmed. By contrast, the effect of heavy metals on activated basophil could not be observed. The difference of constituents (polycyclic aromatic hydrocarbons and heavy metals) in ambient dust by the difference of particle size (total suspended particulate (TSP) and particulate matter 2.5 (PM2.5)) was observed. Seasonal variation of constituents in TSP or PM2.5 was also observed. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:17K00567, 研究期間(年度):2017-04-01 - 2020-03-31 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:「大気粉塵中遷移金属による喘息患者の症状悪化機構の解明」研究成果報告書 課題番号17K00567 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K00567/17K00567seika/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=90190678 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=90190678 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K00567/ | |||||
関連名称 | https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K00567/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K00567/17K00567seika/ | |||||
関連名称 | https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-17K00567/17K00567seika/ |