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マウス消化器がんモデルを用いた悪性化・転移機構の探索
https://doi.org/10.24517/00059509
https://doi.org/10.24517/00059509f8e49665-70a9-40bd-aec4-af021e1e1653
名前 / ファイル | ライセンス | アクション |
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CA-PR-ISHIKAWA-T-kaken 2012-4p.pdf (179.0 kB)
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Item type | 報告書 / Research Paper(1) | |||||
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公開日 | 2020-10-05 | |||||
タイトル | ||||||
タイトル | マウス消化器がんモデルを用いた悪性化・転移機構の探索 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Research of the mechanisms of progression and metastasis using mouse gastrointestinal cancer models | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_18ws | |||||
資源タイプ | research report | |||||
ID登録 | ||||||
ID登録 | 10.24517/00059509 | |||||
ID登録タイプ | JaLC | |||||
著者 |
石川, 智夫
× 石川, 智夫 |
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著者別表示 |
Ishikawa, Tomoo
× Ishikawa, Tomoo |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学がん進展制御研究所 | |||||
書誌情報 |
平成23(2011)年度 科学研究費補助金 研究活動スタート支援 研究成果報告書 en : 2011 Fiscal Year Final Research Report 巻 2010 – 2011, p. 4p., 発行日 2012-04-04 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 消化器がんの死亡原因となる悪性化、転移のメカニズムを解析するために、マウスの腫瘍形成モデルを用いた新しい実験系の構築を試みた。その結果、胃腫瘍、腸腫瘍を発生する遺伝子改変マウス、化学発がんモデルマウスよりの腫瘍細胞の単離、経代培養を行った。また、これらの細胞への遺伝子導入、発現も可能となり、悪性化・転移を示す形質の変化を誘導する新たな因子の同定につながる結果を得た。 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To analyze the mechanisms of gastrointestinal cancer progression and metastasis which result in many patient death, tumor cells from mouse genetic models were used to establish a new in vitro system. Tumor cells were isolated from genetic and chemical mouse models for gastric and intestinal tumor formation, cultured and passaged. Transfection of expression vector was also possible in these cells. This system can be utilized for the identification of candidate genes which relate to cancer progression and metastasis. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 研究課題/領域番号:22800025, 研究期間(年度):2010-2011 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 出典:研究課題「マウス消化器がんモデルを用いた悪性化・転移機構の探索」課題番号22800025 (KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-22800025/22800025seika/)を加工して作成 |
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著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/search/?qm=70322162 | |||||
関連名称 | https://kaken.nii.ac.jp/search/?qm=70322162 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22800025/ | |||||
関連名称 | https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-22800025/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-22800025/22800025seika/ | |||||
関連名称 | https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-22800025/22800025seika/ |