2026-03-15T20:57:09Z https://kanazawa-u.repo.nii.ac.jp/oai

oai:kanazawa-u.repo.nii.ac.jp:00031255 2024-06-27T01:25:16Z 2268:2269:2270

Well-designed bone-seeking radiolabeled compounds for diagnosis and therapy of bone metastases 小川, 数馬 30347471 Ogawa, Kazuma Ishizaki, Atsushi Bone-seeking radiopharmaceuticals are frequently used as diagnostic agents in nuclear medicine, because they can detect bone disorders before anatomical changes occur. Furthermore, their effectiveness in the palliation of metastatic bone cancer pain has been demonstrated in the clinical setting. With the aim of developing superior bone-seeking radiopharmaceuticals, many compounds have been designed, prepared, and evaluated. Here, several well-designed bone-seeking compounds used for diagnostic and therapeutic use, having the concept of radiometal complexes conjugated to carrier molecules to bone, are reviewed. © 2015 Kazuma Ogawa and Atsushi Ishizaki. 金沢大学新学術創成研究機構 / 金沢大学医薬保健研究域薬学系 Hindawi Publishing Corporation 2015-01-01 2017-10-05 eng journal article VoR https://doi.org/10.24517/00031242 http://hdl.handle.net/2297/43011 https://kanazawa-u.repo.nii.ac.jp/records/31255 10.24517/00031242 10.1155/2015/676053 http://www.hindawi.com/journals/bmri/2015/676053/ 2314-6133 BioMed Research International 2015 676053 https://kanazawa-u.repo.nii.ac.jp/record/31255/files/FR-PR-OGAWA-K-676053.pdf application/pdf 2.4 MB 2017-10-05