@article{oai:kanazawa-u.repo.nii.ac.jp:00010451,
 author = {Igarashi, Kiyohiko and Uchihashi, Takayuki and Samejima, Masahiro and Ando, Toshio and 五十嵐, 圭日子 and 内橋, 貴之 and 鮫島, 正浩 and 安藤, 敏夫},
 issue = {3},
 journal = {生物物理 = Biophysics},
 month = {Jan},
 note = {We carried out the real-time visualization of individual cellulase molecules using a high-speed atomic force microscopy (HS-AFM), having sub-second time resolution and nanometer space resolution. Trichoderma reesei cellobiohydrolase I (TrCel7A) molecules were observed to slide unidirectionally along the crystalline cellulose surface, and the catalytic domain without the cellulose-binding domain moved with a velocity similar to that of the intact TrCel7A enzyme although inactive mutant did not move, indicating a processive movement of the enzyme driven by the hydrolytic reaction. We also observed traffic jam of enzyme molecules and synergistic degradation of crystalline cellulose using HS-AFM., 金沢大学ナノ生命科学研究所 / 金沢大学理工研究域数物科学系},
 pages = {140--144},
 title = {高速原子間力顕微鏡による結晶性セルロース酵素分解のリアルタイム1分子イメージング},
 volume = {53},
 year = {2013}
}