@article{oai:kanazawa-u.repo.nii.ac.jp:00010586, author = {添田, 貴宏 and 藤波, 修平 and 猪股, 勝彦 and 宇梶, 裕 and Miyamoto, Yoshiaki and Wada, Norihiro and Soeta, Takahiro and Fujinami, Shuhei and Inomata, Katsuhiko and Ukaji, Yutaka}, issue = {4}, journal = {Chemistry - An Asian Journal}, month = {Apr}, note = {The stereoselective direct transformation of N-(propargylic)hydroxylamines into cis-2-acylaziridines was achieved by the combined use of AgBF4 and CuCl. Copper salts were found to promote the transformation of the intermediary 4-isoxazolines into 2-acylaziridines and both 3-aryl- and 3-alkyl-substituted 2-acylaziridines could be prepared by using this method. Furthermore, subsequent 1,3-dipolar cycloaddition of azomethine ylides that were generated in situ from the intermediary 2-acylaziridines with maleimides was achieved in a stereoselective one-pot procedure to afford the corresponding 2-acylpyrrolidines, which consisted of an octahydropyrrolo[3,4-c]pyrrole skeleton. Love the way ylide: The transformation of N-(propargylic) hydroxylamines into cis-2-acylaziridines and subsequent 1,3-dipolar cycloaddition of the in situ generated azomethine ylides with maleimides stereoselectively afforded 2-acylpyrrolidines. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.}, pages = {824--831}, title = {One-pot stereoselective synthesis of 2-acylaziridines and 2-acylpyrrolidines from N-(propargylic)hydroxylamines}, volume = {8}, year = {2013} }