@article{oai:kanazawa-u.repo.nii.ac.jp:00010590, author = {添田, 貴宏 and 遠藤, 恆平 and 藤波, 修平 and 宇梶, 裕 and Sakai, Takahiro and Soeta, Takahiro and Endo, Kohei and Fujinami, Shuhei and Ukaji, Yutaka}, issue = {10}, journal = {Organic Letters}, month = {May}, note = {An asymmetric Strecker-type reaction of nitrones using acetone cyanohydrin as a source of HCN has been realized. A magnesium-tartramide complex, generated from (R,R)-2,3-dihydroxy-1,4-di(pyrrolidin-1-yl)-butane-1,4-dione and MeMgBr, promoted transcyanation from the bromomagnesium salt of the cyanohydrin, in the presence of a catalytic amount of DBU, to afford the corresponding optically active (S)-α-amino nitrile derivatives. The reaction was applicable to various nitrones giving high-to-excellent enantioselectivities. © 2013 American Chemical Society.}, pages = {2422--2425}, title = {Magnesium-tartramide complex mediated asymmetric Strecker-type reaction of nitrones using cyanohydrin}, volume = {15}, year = {2013} }