@article{oai:kanazawa-u.repo.nii.ac.jp:00010782, author = {藤波, 修平 and 猪股, 勝彦 and 宇梶, 裕 and Yonezawa, Yasushi and Furuya, Tomoki and Aratani, Takahiro and Fujinami, Shuhei and Inomata, Katsuhiko and Ukaji, Yutaka}, issue = {12}, journal = {Tetrahedron Asymmetry}, month = {Jun}, note = {Desymmetrization of various meso-methylenecyclopropanes was accomplished by a palladium-catalyzed asymmetric ring-opening bis(alkoxycarbonylation) reaction employing a chiral bioxazoline ligand. The reaction proceeded smoothly in the presence of copper(I) triflate under carbon monoxide and oxygen at ambient pressure to give the corresponding optically active α-methyleneglutarates with up to 60% ee. Desymmetrization of protected meso-(3-methylenecyclopropane- 1,2-diyl)dimethanols was also carried out to give enantioenriched highly oxygen-functionalized α-methyleneglutarates. © 2014 Elsevier Ltd. All rights reserved.}, pages = {936--943}, title = {Desymmetrization of meso-methylenecyclopropanes by a palladium-catalyzed asymmetric ring-opening bis(alkoxycarbonylation) reaction}, volume = {25}, year = {2014} }