@article{oai:kanazawa-u.repo.nii.ac.jp:00010923,
 author = {Elmogy, Mohamed and Terashima, Jun and Iga, Masatoshi and Iwami, Masafumi and Sakurai, Sho},
 issue = {8},
 journal = {Zoological science},
 month = {Aug},
 note = {In the anterior silk glands (ASGs) of the silkworm, Bombyx mori, intracellular cAMP increases transiently to a very high level shortly after the hemolymph ecdysteroid peak in the prepupal period. In cultured ASGs obtained on the day of gut-purge, cAMP levels were increased by 20-hydroxy-ecdysone (20E), and this increase was enhanced by an inhibitor of phosphodiesterase, but was not affected by α-amanitin, indicating the 20E action may not be mediated via gene expression. The increase in cAMP occurred within 30 seconds of exposure to a physiological concentration of 20E (1 μM), and also by ponasterone A. Our findings indicate a nongenomic action of ecdysteroids in insects, which may be an additional mechanism by which this steroid hormone induces acute responses in tissues and cells. © 2006 Zoological Society of Japan.},
 pages = {715--719},
 title = {A rapid increase in cAMP in response to 20-hydroxyecdysone in the anterior silk glands of the silkworm, Bombyx mori},
 volume = {23},
 year = {2006}
}