{"created":"2023-07-27T06:28:25.079314+00:00","id":12970,"links":{},"metadata":{"_buckets":{"deposit":"0c94cac8-22ba-4746-a98b-e753268f95b3"},"_deposit":{"created_by":3,"id":"12970","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"12970"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00012970","sets":["1132:1133:1134"]},"author_link":["20187","234","71","584","20193","20186","20190","605","20185","20191","20189","20192","20188"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"160","bibliographicPageStart":"157","bibliographicVolumeNumber":"78","bibliographic_titles":[{"bibliographic_title":"European Journal of Haematology"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Human leukocyte antigen (HLA)-mismatched stem cell transplantation from non-inherited maternal antigen (NIMA)-complementary donors is known to produce stable engraftment without inducing severe graft-versus-host disease (GVHD). We treated two patients with acute myeloid leukemia (AML) and one patient with severe aplastic anemia (SAA) with HLA-mismatched stem cell transplantation (SCT) from NIMA-complementary donors (NIMA-mismatched SCT). The presence of donor and recipient-derived blood cells in the peripheral blood of recipient (donor microchimerism) and donor was documented respectively by amplifying NIMA-derived DNA in two of the three patients. Graft rejection occurred in the SAA patient who was conditioned with a fludarabine-based regimen. Grade III and grade IV acute GVHD developed in patients with AML on day 8 and day 11 respectively, and became a direct cause of death in one patient. The findings suggest that intensive conditioning and immunosuppression after stem cell transplantation are needed in NIMA-mismatched SCT even if donor and recipient microchimerisms is detectable in the donor and recipient before SCT. © 2007 The Authors.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学大学院医学系研究科機能再生学","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier BV"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/j.1600-0609.2006.00797.x","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0902-4441","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Okumura, Hirokazu"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Masaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kotani, Takeharu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugimori, Naomi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugimori, Chiharu"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Ozaki, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kondo, Yukio"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Yamazaki, Hirohito"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Chuhjo, Tatsuya"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Takami, Akiyoshi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Ueda, Mikio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohtake, Shigeki"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Nakao, Shinji"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-OKUMURA-H-797.pdf","filesize":[{"value":"149.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-OKUMURA-H-797.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/12970/files/ME-PR-OKUMURA-H-797.pdf"},"version_id":"638809f7-c788-4acf-bf92-d4eb4f15d16e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Graft rejection and hyperacute graft-versus-host disease in stem cell transplantation from non-inherited maternal antigen complementary HLA-mismatched siblings","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Graft rejection and hyperacute graft-versus-host disease in stem cell transplantation from non-inherited maternal antigen complementary HLA-mismatched siblings"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"12970","relation_version_is_last":true,"title":["Graft rejection and hyperacute graft-versus-host disease in stem cell transplantation from non-inherited maternal antigen complementary HLA-mismatched siblings"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T11:52:20.447367+00:00"}