@article{oai:kanazawa-u.repo.nii.ac.jp:00012989,
 author = {Itoh, Hideki and Namura, Masanobu and Seki, Hiroyuki and Asai, Toru and Tsuchiya, Taketsugu and Uenishi, Hiroaki and Fujii, Hiroyuki and Fujita, Shinichiro and Tanabe, Yujirou and Ito, Jun and Shimizu, Masami and Mabuchi, Hiroshi},
 issue = {4},
 journal = {Circulation Journal},
 month = {Jan},
 note = {In areas of severe asynergy, the clinically important task is to identify functionally recoverable myocardium. Fourteen patients with asynergy were investigated by H215O dynamic positron emission tomography imaging before revascularization. Regional myocardial blood flow (MBF) was determined and the water-perfusable tissue fraction (PTF) for each region of interest and the total anatomical tissue fraction (ATF) were estimated. The PTF/ATF was analyzed as the water perfusable tissue index (PTI). Asynergy was defined as segments with wall motion more than 2 SD below than that of a normal population. An increase of >0.8 SD in anterior wall segments with asynergy and an increase of >0.6 SD in inferior wall asynergy were defined as significant improvements of wall motion indicative of viable myocardium. Fifteen segments with wall motion abnormalities less than -2 SD and 10 control segments were identified; 7 segments recovered and 8 segments did not. MBF was similar in both groups of segments before revascularization (0.78±0.27 vs 0.73±0.18 ml · min-1 · g-1, NS). The PTI in the recovered segments was significantly higher than that in the unimproved segments (0.734±0.058 vs 0.592±0.038, p<0.0001) and was similar to that of the control segments. After revascularization, the PTI correlated with the SD of wall motion (p<0.05, r=0.58). PTI may be a good predictor of contractile recovery after revascularization., 金沢大学大学院医学系研究科},
 pages = {341--344},
 title = {Perfusable tissue index obtained by positron emission tomography as a marker of myocardial viability in patients with ischemic ventricular dysfunction},
 volume = {66},
 year = {2002}
}