{"created":"2023-07-27T06:28:26.276297+00:00","id":12998,"links":{},"metadata":{"_buckets":{"deposit":"9777ee72-1ce9-46df-92a6-674309592608"},"_deposit":{"created_by":3,"id":"12998","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"12998"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00012998","sets":["1132:1133:1134"]},"author_link":["20081","20312","20109"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-05-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"113","bibliographicPageStart":"108","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"理学療法学"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"荷重が廃用性筋萎縮の進行抑制に及ぼす効果を, 週内頻度(隔日と毎日)の違いから検討した。24匹のラットを4群に分けた。実験群は(1)2週間の寡運動(非荷重)中に荷重しない群, (2)寡運動中に1時間荷重を隔日に加えた群, (3)寡運動中に1時間荷重を毎日実施した群とし, 1群を対照群とした。その後, ヒラメ筋と長指伸筋を摘出し重量を測定した。さらにATP染色により筋線維タイプを分類(I・II)し, 断面積を測定した。その結果, (1)非荷重および荷重による影響は, 長指伸筋よりヒラメ筋で著明であった。(2)ヒラメ筋の相対重量比およびタイプ構成比率は, 毎日1時間荷重することで維持可能であった。(3)ヒラメ筋断面積は, 荷重しないより隔日, 隔日より毎日荷重の方が有意に大きかった。以上より, 一日1時間の荷重は, 廃用性筋萎縮の進行抑制が可能であり, 隔日荷重より毎日荷重の方が効果的なことが示唆された。 The purpose of this study was to investigate the effect of weight-bearing frequency in a week in prevention of disuse muscular atrophy. Hindlimb suspension (HS) was used to produce muscular atrophy in Wistar rats (n=24). Weight-bearing (WB) was stationary ground support (1 hour/day). Groups were 1) HS only, 2) HS+WB (every other day), 3) HS+WB (everyday), and 4) control. After 2 weeks, right soleus muscle (SOL) and extensor digitorum longus muscle (EDL) were weighed. Muscle ATPase histochemical staining, followed by morphometrical analysis, demonstrated that SOL responded more markedly to non-WB and WB than EDL. The muscle-to-body weight ratio and the percentage distribution of muscle fiber type in SOL were maintained by everyday WB. Muscular atrophy could not be prevented perfectly. But cross-sectional area in SOL indicated that it is possible to delay the progression of disuse muscular atrophy by WB (1 hour/day), and that everyday WB is more effective compared with every other day WB.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学大学院医学系研究科活動能力回復学","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本理学療法士協会"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110004007937/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"本文データは日本理学療法士協会の許諾に基づきCiNiiから複製したものである"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11545224","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0289-3770","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山崎, 俊明"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"灰田, 信英"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"立野, 勝彦"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-YAMAZAKI-T-108.pdf","filesize":[{"value":"995.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-YAMAZAKI-T-108.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/12998/files/ME-PR-YAMAZAKI-T-108.pdf"},"version_id":"3c115230-fe05-4f18-a204-b01ce4f74a3c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"荷重がラット後肢筋の廃用性萎縮予防に及ぼす効果 : 週内頻度からの検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"荷重がラット後肢筋の廃用性萎縮予防に及ぼす効果 : 週内頻度からの検討"},{"subitem_title":"Effect of Weight-Bearing in Prevention of Disuse Atrophy in Rat Hindlimb Muscles : Study of Weight-Bearing Frequency in a Week","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"12998","relation_version_is_last":true,"title":["荷重がラット後肢筋の廃用性萎縮予防に及ぼす効果 : 週内頻度からの検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T01:11:47.348199+00:00"}