@article{oai:kanazawa-u.repo.nii.ac.jp:00013037,
 author = {Onoguchi, Masahisa and Maruno, Hirotaka and Fujinaga, Tsuyoshi and Komiyama, Nobuyuki and Takayama, Teruhiko and Murata, Hajime},
 issue = {3},
 journal = {Journal of Nuclear Medicine Technology},
 month = {Sep},
 note = {Technetium-99m-MlBI uptake was compared between ECG-gated and ungated SPECT images in 10 normal subjects and 10 patients with coronary artery disease to investigate the effects of wall motion on regional myocardial uptake. Methods: Left ventricular ejection fraction (LVEF) and wall motion were evaluated using the first-pass data acquired immediately after injection of 1110 MBq 99mTc-MIBI. A transaxial ungated image was reconstructed with cumulative data during a cardiac cycle. For transaxial gated images, data during a cardiac cycle were divided into eight frames and the first seven frames were used. The lateral/septal ratios for ungated and gated images were obtained using the counts in the ROIs drawn in the lateral and the septal walls. Results: In 10 normal subjects, the lateral/septal ratio for gated increased during end-systole. The mean of the lateral/septal ratio was significantly lower for ungated than for gated (1.025 vs. 1.077, p < 0.05). In patients with septal wall asynergy and a normokinetic lateral wall, the mean of the lateral/septal ratios was significantly lower for ungated than for gated (1.267 vs. 1.325, p < 0.01). Conclusion: Ungated SPECT acquisition may underestimate regional myocardial uptake when myocardial wall motion is good, therefore, ECG-gated data should be acquired for accurate assessment of regional myocardial uptake of 99mTc-MIBI., 金沢大学大学院医学系研究科量子医療技術学},
 pages = {181--186},
 title = {Comparison of regional myocardial Technetium-99m-MIBI uptake between ECG-gated and ungated SPECT imaging},
 volume = {25},
 year = {1997}
}