@article{oai:kanazawa-u.repo.nii.ac.jp:00013076, author = {山本, 美由紀 and 井関, 尚一}, issue = {4}, journal = {Acta Histochemica et Cytochemica}, month = {Jan}, note = {The expression and localization of NGF and its high-affinity receptor, TrkA, in the rat carotid body was investigated by use of in situ hybridization and immunohistochemistry, respectively. The immunoreactivity for TrkA was detected in most of chief cells and sustentacular cells, as well as in some nerve axons and perineurial cells, but not in Schwann cells. In electron microscopy, the immunoreactivity was localized to the cytoplasm. The mRNA for NGF was localized to most of chief cells and possibly also to sustentacular cells. These results demonstrated that carotid body chief cells, having the neural crest origin, produce both NGF and TrkA, implying a paracrine-autocrine role of NGF in the carotid body., 金沢大学大学院医学系研究科がん細胞学}, pages = {377--383}, title = {Co-expression of NGF and Its High-affinity Receptor TrkA in the Rat Carotid Body Chief Cells}, volume = {36}, year = {2003} }