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Past administration of β-lactam antibiotics and increase in the emergence of β-lactamase-producing bacteria in patients with orofacial odontogenic infections.
http://hdl.handle.net/2297/2457
http://hdl.handle.net/2297/2457daeb55bf-278c-4466-adb8-523275748e9a
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Past administration of β-lactam antibiotics and increase in the emergence of β-lactamase-producing bacteria in patients with orofacial odontogenic infections. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kuriyama, Tomoari
× Kuriyama, Tomoari× Nakagawa, Kiyomasa× Karasawa, Tadahiro× Saiki, Yasumasa× Yamamoto, Etsuhide× Nakamura, Shinichi |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学大学院医学系研究科 | |||||
書誌情報 |
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 巻 89, 号 2, p. 186-192, 発行日 2000-02-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1079-2104 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1067/moe.2000.102040 | |||||
出版者 | ||||||
出版者 | Elsevier | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective. The purpose of this study was to determine the current status of β-lactamase–producing bacteria in orofacial odontogenic infections. Study design. Microbiologic data regarding purulent exudate from 111 cases with orofacial odontogenic infections were analyzed in relation to the past administration of β-lactams. Results. β-lactamase–producing bacteria were isolated more frequently from the β-lactam-administered group (38.5%) than from the β-lactam-nonadministered group (10.9%; P < .005), and they were isolated more frequently as the duration of administration increased. The predominant bacteria isolated included Prevotella (the most frequent isolate), viridans streptococci, Peptostreptococcus , and Fusobacterium , and 7.1% of total isolates produced β-lactamase. Penicillin and cefazolin worked well with β-lactamase–nonproducing Prevotella but were remarkably affected by β-lactamase–producing Prevotella . Cefmetazole, sulbactam/cefoperazone, and imipenem worked well against both types of Prevotella . Conclusions. β-lactams are still suitable for the first antimicrobial therapy in the treatment of these infections. However, because past β-lactam administration increases the emergence of β-lactamase–producing bacteria, β-lactamase-stable antibiotics should be prescribed to patients with unresolved infections who have received β-lactams.(Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:186-92) | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |