{"created":"2023-07-27T06:28:42.733185+00:00","id":13296,"links":{},"metadata":{"_buckets":{"deposit":"78a24994-7d71-432f-a489-b72eaeaf9028"},"_deposit":{"created_by":3,"id":"13296","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13296"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00013296","sets":["1132:1133:1134"]},"author_link":["438","21531","21528","21532","477","265","21530","21527","539","21529"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"754","bibliographicPageStart":"748","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Metabolism: Clinical and Experimental"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We investigated the relative impacts of visceral adiposity and insulin resistance on the metabolic risk profile in middle-aged Japanese men. A cross-sectional study was conducted in 636 nondiabetic Japanese men with a mean age of 51.6 years. Visceral adipose tissue (AT) was assessed using computed tomography, and insulin resistance was determined by the homeostasis model assessment of insulin resistance (HOMA-IR). Metabolic risk factors were diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III metabolic syndrome criteria: (1) hypertriglyceridemia, (2) low high-density lipoprotein cholesterol, (3) hypertension, (4) impaired fasting glucose, and (5) impaired glucose tolerance. Visceral AT and HOMA-IR were significantly and positively correlated with each other (r = 0.41, P < .001). Using the 75th percentile value as a cut point, those with isolated large visceral AT showed significantly greater odds ratios for each of the 5 risk factors measured except impaired fasting glucose, whereas those with isolated high HOMA-IR showed significantly greater odds ratios for each of the 5 risk factors except hypertriglyceridemia and impaired glucose tolerance, compared with the control group. The combined group (increased visceral AT and HOMA-IR) had the highest odds ratios for all studied risk factors. On logistic regression analysis using visceral AT and HOMA-IR as continuous independent variables, they were each independently associated with most of the metabolic risk factors and their clustering. In conclusion, neither visceral AT nor HOMA-IR stands out as the sole driving force of the risk profile; each makes a significant contribution to metabolic abnormalities in Japanese men. © 2010 Elsevier Inc. All rights reserved.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学大学院医学系研究科","subitem_description_type":"Other"},{"subitem_description":"北陸中央病院内科","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.metabol.2009.09.020","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.elsevier.com/locate/issn/00260495","subitem_relation_type_select":"URI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA0073583X","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0026-0495","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oka, Rie"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kobayashi, Junji"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Inazu, Akihiro"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Yagi, Kunimasa"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Miyamoto, Susumu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakurai, Masaru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Koshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miura, Katsuyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakagawa, Hideaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamagishi, Masakazu"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-OKA-R-748.pdf","filesize":[{"value":"314.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-OKA-R-748.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/13296/files/ME-PR-OKA-R-748.pdf"},"version_id":"4431640d-aa0c-41e3-aec4-2788d253596e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Contribution of visceral adiposity and insulin resistance to metabolic risk factors in Japanese men","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Contribution of visceral adiposity and insulin resistance to metabolic risk factors in Japanese men"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"13296","relation_version_is_last":true,"title":["Contribution of visceral adiposity and insulin resistance to metabolic risk factors in Japanese men"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T01:07:41.323400+00:00"}