{"created":"2023-07-27T06:28:44.301341+00:00","id":13320,"links":{},"metadata":{"_buckets":{"deposit":"37ce8893-db00-409e-83f3-cc046919f61e"},"_deposit":{"created_by":3,"id":"13320","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13320"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00013320","sets":["1132:1133:1134"]},"author_link":["21634","15223","21630","21632","21635","21633","21631","21636","62","225","99"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"759","bibliographicPageStart":"753","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"Diabetic Medicine"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aims This study investigated the relationship between waist circumference and the subsequent incidence of Type 2 diabetes and the association with insulin resistance and pancreatic B-cell function in relatively lean Japanese individuals. Methods The study participants were 3992 employees (2533 men and 1459 women, aged 35-55 years) of a metal-products factory in Japan. The incidence of diabetes was determined in annual medical examinations during an 8-year follow-up. We calculated age- and sex-adjusted hazard ratios (HRs) according to the sex-specific quintile of waist circumference at baseline. Differences in baseline insulin resistance [homeostatis model assessment (HOMA)-IR] and pancreatic B-cell function (HOMA-B) were compared between participants who developed diabetes and those who did not. Results During the follow-up, 218 participants developed diabetes. Age- and sex-adjusted HRs across the quintiles of waist circumference were 1.78, 1.00 (reference), 1.59, 3.11 and 3.30, respectively (P for trend, < 0.0001). The HR for the lowest quintile was significantly higher than that for the second quintile. Among participants with waist circumference of the lowest quintile, HOMA-B was lower in those who developed diabetes than in those who did not [33.1 (24.1-45.0) vs. 54.3 (37.9-74.6) median (interquartile range), P < 0.0001], but HOMA-IR did not differ between these groups. Conclusions There was a J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes in relatively lean Japanese individuals; lower pancreatic B-cell function may also increase the risk of diabetes in very lean Japanese people. © 2009 Diabetes UK.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"},{"subitem_description":"金沢医科大学健康増進予防医学（公衆衛生学）","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Blackwell Publishing"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1111/j.1464-5491.2009.02773.x","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA1063816X","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0742-3071","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sakurai, Sho"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Miura, K."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takamura, Toshinari"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Ishizaki, Masao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morikawa, Y."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, K."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshita, Katsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kido, Teruhiko"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Naruse, Yuchi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kaneko, Shuichi"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Nakagawa, H."}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-SAKURAI-M-753.pdf","filesize":[{"value":"280.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-SAKURAI-M-753.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/13320/files/ME-PR-SAKURAI-M-753.pdf"},"version_id":"639e5bf0-f1f0-4e76-9f48-a60ac9ca08cd"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes: An 8-year follow-up of relatively lean Japanese individuals","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes: An 8-year follow-up of relatively lean Japanese individuals"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"13320","relation_version_is_last":true,"title":["J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes: An 8-year follow-up of relatively lean Japanese individuals"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T01:07:18.008506+00:00"}