@article{oai:kanazawa-u.repo.nii.ac.jp:00013325,
 author = {Sakai, Asao and Iwasa, Keiichi and Maeda, Yoshinobu and Kimura, Hideharu and Kasahara, Kazuo and Fujimura, Masaki},
 issue = {6},
 journal = {Japanese Journal of Lung Cancer = 肺癌},
 month = {Oct},
 note = {Background. Even though the head and neck are common metastatic sites in lung cancer patients, paranasal metastases are rare. We report a patient with lung cancer who had paranasal sinus metastases. Case. A 56-year-old man with lung cancer presented with nasal hemorrhage 1.5 years after the initiation of chemotherapy. On CT, mass shadows were seen in bilateral frontal sinuses, maxillary antra, the left ethmoidal sinus, the sphenoidal sinus, and the nasal cavity. Biopsies of the lesion in the nasal cavity showed adenocarcinoma, confirming that the lesions in the paranasal sinuses were lung cancer metastases. The cranial MRI done at the time of the first admission was reviewed, and a small nodule was found in left ethmoidal sinus. Conclusion. Paranasal sinus metastases are found in a patient with NSCLC who don't have symptoms related to the paranasal sites. Paranasal sites should be carefully evaluated in patients with advanced NSCLC. © 2008 The Japan Lung Cancer Society.　　　[背景]肺癌の頭頸部への転移は比較的高い頻度で認められるが、副鼻腔転移は極めて稀である。今回われわれは、経過中に副鼻腔転移を認めた症例を経験した。[症例]症例は56歳、男性。1年半にわたる肺癌治療経過中に鼻出血が出現した。頭部CTでは両側前頭洞、左側篩骨洞・上顎洞・鼻腔にかけて腫瘤性病変を認めた。生検による病理組織像は原発巣と同一の腺癌であった。初回入院時の頭部MRIをレトロスペクティブに検討したところ、左篩骨洞に腫瘤陰影があり、初診時にすでに副鼻腔転移を認めていたものと考えられた。[結論]副鼻腔転移は治療経過中に認められる報告が多いが、初診時にも無症状の副鼻腔転移を有する場合があり、慎重に診断して観察する必要がある。全文公開201010, 金沢大学大学院医学系研究科細胞移植学講座},
 pages = {715--720},
 title = {副鼻腔転移をきたした肺腺癌の1例},
 volume = {48},
 year = {2008}
}