@article{oai:kanazawa-u.repo.nii.ac.jp:00013392,
 author = {Edahiro, Shigeki and Yoshikawa, Hiroaki and Iwasa, Kazuo and Hashii, Minako and Yamada, Masahito},
 issue = {6},
 journal = {Biomedical Research},
 month = {Dec},
 note = {TE671 is a cell line obtained from the rhabdomyosarcoma cells. In the present study, we examined [Ca2+]i alteration induced by acetylcholine (ACh) in TE671/RD cells with the special attention to ryanodine receptor (RyR) and inositol 1,4,5-triphosphate receptor (IP3R). The change of [Ca2+]i was mediated by muscarinic type 3 (m3) AChR. Both phosphatidylinositol-specific phospholipase C blocker (U73122) and IP3R blocker (2-APB) inhibited ACh-induced [Ca2+]i elevation, suggesting that IP3 pathway is involved in [Ca2+]i alteration. Ryanodine and FK506 increased ACh-induced [Ca2+]i elevation, which was decreased by RyR blocker (ruthenium red). These results suggest that RyR and FK506 binding protein 12 kDa (FKBP12) complex was involved in [Ca2+]i change, and that TE671/RD cell line has a hybrid characteristic of smooth and skeletal muscles. Copyright © 2005 Biomedical Research Press., 金沢大学医薬保健研究域医学系},
 pages = {255--261},
 title = {Cytosolic Ca2+ alteration mediates both ryanodine receptor and IP3 receptor in TE671/RD cells},
 volume = {25},
 year = {2004}
}