{"created":"2023-07-27T06:28:59.641317+00:00","id":13627,"links":{},"metadata":{"_buckets":{"deposit":"3a5a7c2c-fc97-417a-b67f-6bc20ce6a104"},"_deposit":{"created_by":3,"id":"13627","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13627"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00013627","sets":["1132:1133:1134"]},"author_link":["22693","22694","22692"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-09-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"722","bibliographicPageStart":"717","bibliographicVolumeNumber":"110","bibliographic_titles":[{"bibliographic_title":"日本眼科學会雜誌 = Journal of Japanese Ophthalmological Society"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"広義の原発開放隅角緑内障に対するイソプロピルウノプロストン単独投与による眼圧と視野への影響についてレトロスペクティブに検討した. 2年以上観察した49例80眼のうち, 視力と視野の信頼性が良好な32例32眼を対象とした. 年齢68. 1±10. 1歳, 観察期間47. 8±14. 7か月であった. 眼圧と視野について無治療時と経過中の値を比較した. 視野はKaplan－Meier法による累積生存率も検討した. 投与前眼圧14. 7±4. 3mmHgに対し4年間下降し, 4年後は12. 7±4. 4mmHgであった. 視野（mean defectとloss variance）は, 4年間有意な悪化はなかった. mean defectが3dB悪化した時をend pointとした時の視野の悪化しない確率は, 4年後で80. 7±8. 0％であった. イソプロピルウノプロストンは, 長期間眼圧を下降させ, 視野を維持する可能性があると考えられた. （日眼会誌110：717－722, 2006）　　We retrospectively investigated the long－term effects of isopropyl unoprostone monotherapy on intraocular pressure and visual field for normaltension glaucoma and primary open－angle glaucoma patients. Among 80 eyes of 49 subjects receiving isopropyl unoprostone monotherapy for 2 years or more, 32 eyes of 32 subjects were analyzed because of the good reliability of their visual acuity and visual field（age, 68. 1±10. 1 yrs, follow－up period 47. 8±14. 7 months） . The mean values of intraocular pressure and visual field indices were compared with baseline data before medication. The visual field changes were also analyzed using the Kaplan－Meier life－table method. The mean intraocular pressure decreased for 4 years from 14. 7±4. 3mmHg（mean±SD）at baseline, to 12. 7±4. 4mmHg at 4 years. The global index of visual field（mean defect, loss variance）did not change significantly during the 4 years. The accumulative probability of survival was 80. 7±8. 0％ after 4 years when the endpoint was defined as 3dB progression in mean defect. Isopropyl unoprostone might have the possibility of stabilizing the visual field for a long period of time. Nippon Ganka Gakkai Zasshi（J Jpn Ophthalmol Soc 110：717－722, 2006）","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本眼科学会 = Japanese Ophthalmological Society"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.nichigan.or.jp/member/journal/nggz/index.jsp","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/10018332072/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © Japanese Ophthalmological Society"}]},"item_4_rights_24":{"attribute_name":"権利URI","attribute_value_mlt":[{"subitem_rights":"http://www.nichigan.or.jp/index.jsp"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00187157","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0029-0203","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"齋藤, 代志明"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"佐伯, 智幸"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"杉山, 和久"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-SUGIYAMA-K-717.pdf","filesize":[{"value":"3.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-SUGIYAMA-K-717.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/13627/files/ME-PR-SUGIYAMA-K-717.pdf"},"version_id":"4a65c07a-8edb-486f-8200-8f15b55c49a7"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"広義原発開放隅角緑内障に対するイソプロピルウノプロストン単独投与による眼圧および視野の長期経過","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"広義原発開放隅角緑内障に対するイソプロピルウノプロストン単独投与による眼圧および視野の長期経過"},{"subitem_title":"Long－term Effects of Isopropyl Unoprostone Monotherapy on Intraocular Pressure and Visual Field for Normal－tension Glaucoma and Primary Open－angle Glaucoma Patients","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"13627","relation_version_is_last":true,"title":["広義原発開放隅角緑内障に対するイソプロピルウノプロストン単独投与による眼圧および視野の長期経過"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T01:01:18.020928+00:00"}