@article{oai:kanazawa-u.repo.nii.ac.jp:00013663,
 author = {Araki, Daisuke and Fujii, Hiroshi and Matsumura, Masami and Yamagishi, Masakazu and Yachie, Akihiro and Kawano, Mitsuhiro},
 issue = {17},
 journal = {Internal Medicine},
 month = {Jan},
 note = {Hemophagocytic syndrome (HPS) is a severe, potentially life-threatening disorder characterized by an excessive activation of macrophages, such as may occur in the setting of lupus. A 62-year-old Japanese woman treated with etanercept for rheumatoid arthritis developed persistent fever, cytopenia, coagulopathy, and hyperferritinemia. Simultaneously, lupus-like features including pleuritis, hypocomplementemia, and positive autoantibodies were observed. She was diagnosed with HPS related to etanercept-induced lupus, and underwent immunosuppressive therapy with successful recovery. To our knowledge, this is the first case of etanercept-induced lupus accompanied by HPS. This case suggests that HPS should be considered as a complication during TNF-α inhibitor therapy.},
 pages = {1843--1848},
 title = {Etanercept-Induced Lupus Accompanied by Hemophagocytic Syndrome},
 volume = {50},
 year = {2011}
}