{"created":"2023-07-27T06:29:03.962488+00:00","id":13729,"links":{},"metadata":{"_buckets":{"deposit":"9c95734e-e8c8-4169-8606-172fc817d5dc"},"_deposit":{"created_by":3,"id":"13729","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13729"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00013729","sets":["1132:1133:1134"]},"author_link":["234","22986","22987","22991","22992","22990","22989","22985","22984","514","71","22988"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"464","bibliographicPageStart":"461","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"Leukemia"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Acute myeloid leukemia (AML) with t(6;9)(p23;q34) is well known to have a poor prognosis treated with chemotherapy and autotransplantation. The presence of this karyotype is an indicator for allogeneic hematopoietic stem cell transplantation (HSCT); however, the impact of t(6;9)(p23;q34) on the HSCT outcome remains unclear. We conducted a matched-pair analysis of de novo AML patients with and without t(6;9)(p23;q34) using data obtained from the Japanese HSCT data registry. A total of 57 patients with t(6;9)(p23;q34) received transplants between 1996 and 2007, and 171 of 2056 normal karyotype patients matched for age, disease status at HSCT and graft source were selected. The overall survival, disease-free survival, cumulative incidence of relapse and the non-relapse mortality in t(6;9)(p23;q34) patients were comparable to those for normal karyotype patients. A univariate analysis showed that t(6;9)(p23;q34) had no significant impact on the overall survival. These findings suggest that allogeneic HSCT may overcome the unfavorable impact of t(6;9)(p23;q34) as an independent prognostic factor. © 2012 Macmillan Publishers Limited All rights reserved.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nature Publishing Group"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1038/leu.2011.229","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA10668706","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0887-6924","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ishiyama, Ken"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Takami, Akiyoshi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Kanda, Yoshinobu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakao, Shinji"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Hidaka, Michihiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Tetsuo"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Naoe, Tomoki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taniguchi, Shuichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawa, Keisei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagamura, Tokiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Atsuta, Yoshiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakamaki, Hisashi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-ISHIYAMA-K-461.pdf","filesize":[{"value":"444.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-ISHIYAMA-K-461.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/13729/files/ME-PR-ISHIYAMA-K-461.pdf"},"version_id":"1958b742-12ee-4c01-ad4a-073d945e613d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with t(6;9)(p23;q34) dramatically improves the patient prognosis: A matched-pair analysis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with t(6;9)(p23;q34) dramatically improves the patient prognosis: A matched-pair analysis"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"13729","relation_version_is_last":true,"title":["Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with t(6;9)(p23;q34) dramatically improves the patient prognosis: A matched-pair analysis"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:59:41.379910+00:00"}