{"created":"2023-07-27T06:29:06.946358+00:00","id":13799,"links":{},"metadata":{"_buckets":{"deposit":"5a8eca69-1f31-477c-80ba-5b823d52aadc"},"_deposit":{"created_by":3,"id":"13799","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13799"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00013799","sets":["1132:1133:1134"]},"author_link":["21577","21811","1065","68","20432","507","21301","22001","23211","21810"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"685","bibliographicPageStart":"680","bibliographicVolumeNumber":"37","bibliographic_titles":[{"bibliographic_title":"日本消化器外科学会雑誌 = The Japanese journal of gastroenterological surgery"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は74歳の男性で,眼球黄染と褐色尿を主訴とし入院した.胆道直接造影検査にて下部胆管内腔に乳頭状に突出する腫瘍を認め,胆汁細胞診ではclass V (adenocarcinoma)であったため下部胆管癌と診断した.画像診断上は膵,十二指腸への浸潤はなく,明らかなリンパ節転移,肝転移の所見もなかった.入院当初はendoscopic nasobiliary drainageを行っていたが減黄不良のためpercutaneous transhepatic cholangial drainageに変更し減黄改善を図ったが,次第に肝機能が悪化し,同年7月に肝不全死した.病理解剖の結果,下部胆管内腔に黄色調,乳頭膨張型の腫瘍を認め,肝内に3か所,大網に1か所の転移巣が存在した.病理組織像では,未分化な細胞が充実性に増殖し,免疫染色ではchromogranin A染色,Grimelius染色,CD56染色,CAM染色が陽性で胆管原発小細胞癌と診断された.胆管原発小細胞癌は極めてまれであり,文献的考察を加えて報告した. A 74 year-old man admitted for jaundice was found in diagnostic imaging to have a growing papillary tumor occupying the lumen of the lower bile duct. We diagnosed it as lower bile duct cancer without invasion to other organs, lymph node metastasis, liver metastasis, or distant metastasis, suggesting it could be curatively resected. Though we attempted to improve jaundice before surgery with PTCD, it was persisted and his liver function gradually worsened. He died of liver failure 3 months after admission. Autopsy showed a yellowish expanded papillary tumor in the lower bile duct, 3 metastatic nodules in the liver, and one on the omentum. Histopathological specimens showed undifferentiated round cells arranged crowded or in uncertain gland pattern. In immunohistological studies, granules stained with chromogranin A, Grimelius, CD56, or CAM in the cytoplasm of the cancer cells, and the tumor was diagnosed as small cell carcinoma arising primarily in the common bile duct.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本消化器外科学会 = Japanese Society of Gastroenterological Surgery"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jsgs.or.jp/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/10013673073","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本消化器外科学会 | 本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00192066","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-9768","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"牧野, 勇"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"北川, 裕久"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"太田, 哲生"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"萱原, 正都"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"西村, 元一"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"藤村, 隆"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"清水, 康一"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"三輪, 晃一"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"佐藤, 勝明"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"小田, 惠夫"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-KITAGAWA-H-680.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-KITAGAWA-H-680.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/13799/files/ME-PR-KITAGAWA-H-680.pdf"},"version_id":"b932a28b-72e1-4738-b360-450cc5ca8c6f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"胆管原発小細胞癌の1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胆管原発小細胞癌の1例"},{"subitem_title":"A Case of Primary Small Cell Carcinoma of the Common Bile Duct","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"13799","relation_version_is_last":true,"title":["胆管原発小細胞癌の1例"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:58:29.146276+00:00"}