@article{oai:kanazawa-u.repo.nii.ac.jp:00013889, author = {Tran, Vuong Thi and Ishizaki, Azumi and Nguyen, Cuong Hung and Hoan, Huyen Thi and Pham, Hung Viet and Bi, Xiuqiong and Pham, Thuc Van and Ichimura, Hiroshi}, issue = {10}, journal = {AIDS Research and Human Retroviruses}, month = {Oct}, note = {We reported previously that the prevalence of drug-resistant HIV-1 among antiretroviral therapy (ART)-naive individuals in Northern Vietnam was 2.9% in 2007 and 6.2% in 2008. To investigate the continuing trend of prevalence, we collected plasma samples from 958 individuals in Hai Phong and Hanoi in 2009, extracted viral RNA from HIV-1 antibody-positive samples, and analyzed them genetically. HIV-1 antibody prevalence was 26.8% in injecting drug users (n=302), 13.4% in female sex workers (n=284), 0.5% in blood donors (n=206), and 0.6% in pregnant women (n=166). All HIV-1 strains were CRF01-AE. Nonnucleoside reverse-transcriptase inhibitor resistance mutations were found in two (2.0%) of the 102 successfully analyzed cases (one case with the Y181C and one with the K101E). No nucleoside reverse-transcriptase inhibitor resistance or protease inhibitor resistance mutations were detected. The prevalence of circulating ART-resistant HIV-1 in Northern Vietnam did not increase from 2007 to 2009, although the rate of ART coverage did increase. © 2012, Mary Ann Liebert, Inc.}, pages = {1349--1351}, title = {No increase of drug-resistant HIV type 1 prevalence among drug-naive individuals in northern vietnam}, volume = {28}, year = {2012} }