{"created":"2023-07-27T06:29:23.047444+00:00","id":14171,"links":{},"metadata":{"_buckets":{"deposit":"6fe12e7e-6b37-4386-a8a2-aab4bb1d3b12"},"_deposit":{"created_by":3,"id":"14171","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14171"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014171","sets":["1132:1133:1134"]},"author_link":["23154","449","334"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-10-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"562","bibliographicPageStart":"557","bibliographicVolumeNumber":"88","bibliographic_titles":[{"bibliographic_title":"生化学 = The journal of Japanese Biochemical Society"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"APOBEC3がHIV-1の逆転写のいずれかのプロセスに作用し抗ウイルス活性を示すことが報告されて以来，APOBECタンパク質が新しいタイプの抗ウイルス因子として脚光を浴びることとなった．逆転写を必要とするウイルスで忘れがちなウイルスとしてB型肝炎ウイルス（HBV）がある. APOBEC3のHIV-1への抗ウイルス活性が報告されてまもなく，HBVもやはりAPOBECタンパク質の抗ウイルス活性の標的になることが報告された. HIV-1への抗ウイルス作用と類似するところも多々あるが，HBVは肝細胞特異的感染症であり，感染細胞の核にウイルスエピソームDNAを形成するなど，HBVにユニークな点もある．本稿ではAPOBECタンパク質の抗HBV活性および病態形成との関連を概説する．","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本生化学会 = Japanese Biochemical Society"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.14952/SEIKAGAKU.2016.880557","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jbsoc.or.jp/journal","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jbsoc.or.jp/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://seikagaku.jbsoc.or.jp/10.14952/SEIKAGAKU.2016.880557/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2016 公益社団法人日本生化学会"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00126072","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0037-1017","subitem_source_identifier_type":"ISSN"}]},"item_4_text_2":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"Hepatitis B virus and APOBEC family"},{"subitem_text_value":"特集: DNA/RNA編集研究の新たな眺望"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"村松, 正道"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"喜多村, 晃一"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"若江, 亨祥"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-MURAMATSU-M-557.pdf","filesize":[{"value":"394.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-MURAMATSU-M-557.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14171/files/ME-PR-MURAMATSU-M-557.pdf"},"version_id":"ac32296b-257f-47e3-9f27-548b511e2935"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"B型肝炎ウイルスとAPOBECファミリー","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"B型肝炎ウイルスとAPOBECファミリー"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14171","relation_version_is_last":true,"title":["B型肝炎ウイルスとAPOBECファミリー"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:51:41.611398+00:00"}