{"created":"2023-07-27T06:29:24.449718+00:00","id":14198,"links":{},"metadata":{"_buckets":{"deposit":"b2114d89-88d2-4ba9-a341-2f1228eda491"},"_deposit":{"created_by":3,"id":"14198","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14198"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014198","sets":["1132:1133:1134"]},"author_link":["593","2700","66922","209","61698"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"597","bibliographicPageStart":"590","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Journal of Physical Therapy Science"}]}]},"item_4_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"髙橋　, 郁文"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松﨑, 太郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"細, 正博"}],"nameIdentifiers":[{},{},{},{}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[Purpose] This study was performed to evaluate the long-term histopathological changes in knee-joint components including synovial membrane and joint capsule in a rat model of osteoarthritis (OA) induced by monosodium iodoacetate (MIA). [Subjects and Methods] Fifty male rats were used. OA was induced through intra-articular injection of MIA, and ten rats were randomly allocated to each of five groups induced with OA for 1, 2, 4, 6, or 8 weeks. At the end of each period, the knee components were examined histopathologically. [Results] After 1 and 2 weeks, chondrocytes were weakly stained. After 4 weeks, fibrillation, fissuring, and eburnation were observed, whereas after 6 weeks, chondrocyte clustering and osteophyte formation were detected. In the synovial membrane, the proliferation of spindle-shaped cells and a multilayered structure of the surface cells were observed at 1 and 2 weeks, but the degree of these changes decreased over time. In the joint capsule, a narrowing of the space between collagen fiber bundles was observed at 4–8 weeks. [Conclusion] The long-term histopathological changes of the joint components observed in a rat model of OA induced by MIA were similar to those detected in OA, but differed at specific times and tissues.","subitem_description_type":"Abstract"}]},"item_4_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"出版者照会後に全文公開","subitem_description_type":"Other"}]},"item_4_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00014185","subitem_identifier_reg_type":"JaLC"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Society of Physical Therapy Science = 理学療法科学学会"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1589/jpts.29.590","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/jpts","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://spts.jpn.com/en/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2017 by the Society of Physical Therapy Science. Published by IPEC Inc.　理学療法科学学会"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA10798949","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-5287","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takahashi, Ikufumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuzaki, Taro"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Hoso, Masahiro"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-10"}],"displaytype":"detail","filename":"ME-PR-TAKAHASHI-I-590.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-TAKAHASHI-I-590.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14198/files/ME-PR-TAKAHASHI-I-590.pdf"},"version_id":"73bf1835-bc4f-45fd-b748-986ba2e7b813"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Long-term histopathological developments in knee-joint components in a rat model of osteoarthritis induced by monosodium iodoacetate","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Long-term histopathological developments in knee-joint components in a rat model of osteoarthritis induced by monosodium iodoacetate"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-10"},"publish_date":"2018-05-10","publish_status":"0","recid":"14198","relation_version_is_last":true,"title":["Long-term histopathological developments in knee-joint components in a rat model of osteoarthritis induced by monosodium iodoacetate"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T17:30:47.704349+00:00"}