{"created":"2023-07-27T06:29:28.720613+00:00","id":14264,"links":{},"metadata":{"_buckets":{"deposit":"65b508d8-24a4-4bf8-9902-9a28481509d0"},"_deposit":{"created_by":3,"id":"14264","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14264"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014264","sets":["1132:1133:1134"]},"author_link":["24548","24552","24550","24551","24549","24503","24547","24553"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"463","bibliographicPageStart":"455","bibliographicVolumeNumber":"65","bibliographic_titles":[{"bibliographic_title":"Experimental Animals"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"IL-6 is a cytokine that is involved in various physiological and pathological conditions, and approaches using gain-of-function transgenic animals have contributed in elucidating IL-6 function. However, studies of the multiple functions of IL-6 in vivo are very time consuming because they require the generation of transgenic mice that harbor the gene encoding IL-6 under the control of specific promoters to mimic different pathologies. Here, we report the establishment of a conditional human IL-6 transgenic mouse, LGL-IL6, which conditionally expresses human IL-6 by taking advantage of the well-characterized Cre recombinase drivers.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本実験動物学会 = Japanese Association for Laboratory Animal Science"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1538/expanim.16-0043","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jalas.jp/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/expanim","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2016 Japanese Association for Laboratory Animal Science 日本実験動物学会"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11032321","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-1357","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mori, Taiki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murasawa, Yusuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikai, Rina"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayakawa, Tomoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Hiroyuki"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Ogiso, Noboru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Niida, Shumpei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Ken"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-NAKAMURA-H-455.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-NAKAMURA-H-455.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14264/files/ME-PR-NAKAMURA-H-455.pdf"},"version_id":"3b4f2b2f-afba-4f80-8112-98238c85bff5"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Generation of a transgenic mouse line for conditional expression of human IL-6","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Generation of a transgenic mouse line for conditional expression of human IL-6"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14264","relation_version_is_last":true,"title":["Generation of a transgenic mouse line for conditional expression of human IL-6"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:50:25.758447+00:00"}