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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 10. 学術雑誌掲載論文(医・保健)
  3. 1. 査読済論文(医学・保健)

Adult bile duct strictures: differentiating benign biliary stenosis from cholangiocarcinoma

http://hdl.handle.net/2297/45910
http://hdl.handle.net/2297/45910
356f1872-35d4-4df2-8bcd-55a0c0aa536c
名前 / ファイル ライセンス アクション
ME-PR-HARADA-K-189.pdf ME-PR-HARADA-K-189.pdf (965.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2016-08-29
タイトル
タイトル Adult bile duct strictures: differentiating benign biliary stenosis from cholangiocarcinoma
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Canh, Hiep Nguyen

× Canh, Hiep Nguyen

WEKO 68936

Canh, Hiep Nguyen

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Harada, Kenichi

× Harada, Kenichi

WEKO 182
e-Rad 30283112
金沢大学研究者情報 30283112
研究者番号 30283112

Harada, Kenichi

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書誌情報 Medical Molecular Morphology

巻 49, 号 4, p. 189-202, 発行日 2016-12-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1860-1480
NCID
収録物識別子タイプ NCID
収録物識別子 AA12017629
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1007/s00795-016-0143-6
出版者
出版者 Japanese Society for Clinical Molecular Morphology = 日本臨床分子形態学会 / Springer-Verlag
抄録
内容記述タイプ Abstract
内容記述 Biliary epithelial cells preferentially respond to various insults under chronic pathological conditions leading to reactively atypical changes, hyperplasia, or the development of biliary neoplasms (such as biliary intraepithelial neoplasia, intraductal papillary neoplasm of the bile duct, and cholangiocarcinoma). Moreover, benign biliary strictures can be caused by a variety of disorders (such as IgG4-related sclerosing cholangitis, eosinophilic cholangitis, and follicular cholangitis) and often mimic malignancies, despite their benign nature. In addition, primary sclerosing cholangitis is a well-characterized precursor lesion of cholangiocarcinoma and many other chronic inflammatory disorders increase the risk of malignancies. Because of these factors and the changes in biliary epithelial cells, biliary strictures frequently pose a diagnostic challenge. Although the ability to differentiate neoplastic from non-neoplastic biliary strictures has markedly progressed with the advance in radiological modalities, brush cytology and bile duct biopsy examination remains effective. However, no single modality is adequate to diagnose benign biliary strictures because of the low sensitivity. Therefore, understanding the underlying causes by compiling the entire clinical, laboratory, and imaging data; considering the under-recognized causes; and collaborating between experts in various fields including cytopathologists with multiple approaches is necessary to achieve an accurate diagnosis. © 2016 The Japanese Society for Clinical Molecular Morphology
内容記述
内容記述タイプ Other
内容記述 Embargo Period 12 months
権利
権利情報 The final publication is available at www.springerlink.com/article/10.1007%2Fs00795-016-0143-6
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連URI
識別子タイプ URI
関連識別子 http://www.rinshoudenken.gr.jp/
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