{"created":"2023-07-27T06:29:43.713527+00:00","id":14494,"links":{},"metadata":{"_buckets":{"deposit":"cd343848-d4d0-495a-8427-956a319e56cf"},"_deposit":{"created_by":3,"id":"14494","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14494"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014494","sets":["1132:1133:1134"]},"author_link":["21405","93","62"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"964","bibliographicPageStart":"960","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"Journal of Gastroenterology and Hepatology"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) and chronic liver disease worldwide. Recent developments and advances in HCV replication systems in vitro and in vivo, transgenic animal models, and gene expression profiling approaches have provided novel insights into the mechanisms of HCV replication. They have also helped elucidate host cellular responses, including activated/inactivated signaling pathways, and the relationship between innate immune responses by HCV infection and host genetic traits. However, the mechanisms of hepatocyte malignant transformation induced by HCV infection are still largely unclear, most likely due to the heterogeneity of molecular paths leading to HCC development in each individual. In this review, we summarize recent advances in knowledge about the mechanisms of hepatocarcinogenesis induced by HCV infection. © 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Blackwell Publishing Asia Pty"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1111/j.1440-1746.2011.06723.x","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA10727383","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0815-9319","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamashita, Taro"}],"nameIdentifiers":[{"nameIdentifier":"21405","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90377432","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=90377432"},{"nameIdentifier":"90377432","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000090377432"}]},{"creatorNames":[{"creatorName":"Honda, Masao"}],"nameIdentifiers":[{"nameIdentifier":"93","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00272980","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=00272980"},{"nameIdentifier":"00272980","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=00272980"},{"nameIdentifier":"00272980","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000000272980"}]},{"creatorNames":[{"creatorName":"Kaneko, Shuichi"}],"nameIdentifiers":[{"nameIdentifier":"62","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60185923","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60185923"},{"nameIdentifier":"60185923","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=60185923"},{"nameIdentifier":"60185923","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000060185923"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-KANEKO-S-960.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-KANEKO-S-960.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14494/files/ME-PR-KANEKO-S-960.pdf"},"version_id":"cee9cb3b-7dfd-4412-9cf7-7ba946ca08f8"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14494","relation_version_is_last":true,"title":["Molecular mechanisms of hepatocarcinogenesis in chronic hepatitis C virus infection"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-06-20T07:11:35.732719+00:00"}